ReviewImmune network2025
Role of the Aryl Hydrocarbon Receptor in the Self-Renewal, Differentiation, and Immunomodulation of Adult Stem Cells.
Review in Immune network, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Microbiota-derived metabolites in hematopoietic regulation and disease: mechanisms, context, and therapeutic perspectives.Frontiers in microbiology · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult stem cells are a rare population of undifferentiated cells present in almost all body tissues. Depending on their location, stem cells can differentiate into various tissue types, primarily contributing to maintenance, repair, and immune system regulation. Stem cell therapies have significant potential in regenerative medicine and treatment of inflammatory diseases. However, many factors must be considered for successful clinical commercialization, including enhancing therapeutic potential, ensuring product differentiation, and optimizing the manufacturing process for large-scale production. The development of sophisticated regulatory mechanisms may enhance therapeutic applications. The aryl hydrocarbon receptor (AhR) is expressed in all adult stem cells, and its activation and function are tightly regulated. Understanding the role and regulation of AhR is crucial for developing effective stem cell therapies. This review examines the role of the AhR in regulating the fundamental characteristics of adult stem cells, which may contribute to advancing adult stem cell therapies.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.