Evidence map›Paper›PMID 40342838›Full record

ArticleImmune network2025

Patients With Mild COVID-19 Exhibit Low Functional Avidity of SARS-CoV-2 Membrane Protein-Reactive CD4

A-Reum Kim, June-Young Koh, Min-Seok Rha, Jae Hyung Jung, Jae-Hoon Ko, Hee Kyoung Choi, Ji Hoon Jeon, Hyeri Seok, Dae Won Park, Kyong Ran Peck and 5 more

Abstract read
In one paragraph

Article in Immune network, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

A-Reum KimThe Center for Viral Immunology, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon 34126, Korea.ORCID https://orcid.org/0000-0002-6434-4107
June-Young KohGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-2043-6624
Min-Seok RhaGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-1426-7534
Jae Hyung JungGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-6783-813X
Jae-Hoon KoDivision of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.ORCID https://orcid.org/0000-0002-9490-6609
Hee Kyoung ChoiDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea.ORCID https://orcid.org/0000-0003-3140-1336
Ji Hoon JeonDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea.ORCID https://orcid.org/0000-0002-7535-1679
Hyeri SeokDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea.ORCID https://orcid.org/0000-0002-2032-9538
Dae Won ParkDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea.ORCID https://orcid.org/0000-0002-7653-686X
Kyong Ran PeckDivision of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.ORCID https://orcid.org/0000-0002-7464-9780
Jun Yong ChoiDepartment of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID https://orcid.org/0000-0002-2775-3315
Su-Hyung ParkGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-6363-7736
Won Suk ChoiDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea.ORCID https://orcid.org/0000-0001-5874-4764
Hye Won JeongDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0002-1063-8476
Eui-Cheol ShinThe Center for Viral Immunology, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon 34126, Korea.ORCID https://orcid.org/0000-0002-6308-9503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-unexposed individuals exhibited an increased frequency of CD4

Indexed as

CD4-positive-T-lymphocytesCOVID-19Cross-reactivityFunctional aviditySARS-CoV-2

Identifiers

PMID40342838
PMCPMC12056292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.