ArticleProceedings of IEEE Sensors. IEEE International Conference on Sensors2024
Microfluidic Platform for Real-Time Impedance Profiling of Transwell-Based Barrier Models.
Article in Proceedings of IEEE Sensors. IEEE International Conference on Sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
We propose a microfluidic platform with integrated microfabricated electrodes for real-time impedance profiling of transwell-based barrier models, which can be subjected to dynamic microfluidic flow. This platform overcomes the limitations of conventional methods that are based on invasive permeability assays and single time-point impedance measurements: It enables continuous, non-invasive monitoring of tissue barrier integrity at high spatial and temporal resolution. We demonstrate the capabilities of our system by continuously monitoring the gradual loss of barrier integrity in upper-airway-tissue models exposed to non-physiological liquid-liquid interface conditions.
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