Evidence map›Paper›PMID 40342597›Full record

SynthesisFrontiers in microbiology2025

Global patterns of antibiotic resistance in group B

Chou-Yi Hsu, Safoura Moradkasani, Muath Suliman, Subasini Uthirapathy, Ahmed Hussein Zwamel, Ahmed Hjazi, Raghav Vashishth, Masoumeh Beig

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Descriptive review: global spectrum of invasive group B streptococcal disease in nonpregnant adults: epidemiology, risk factors and clinical presentations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  4. Article
  5. Draft genome sequence of a multidrug-resistantMicrobiology resource announcements · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Pathogens (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Dairy FarmPathogens (Basel, Switzerland) · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A murine model of adult gastrointestinal colonization by Group BbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chou-Yi HsuThunderbird School of Global Management, Arizona State University Tempe Campus, Phoenix, AZ, United States.
Safoura MoradkasaniDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Muath SulimanDepartment of Laboratory Medicine, School of Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Subasini UthirapathyPharmacy Department Tishk International University Erbil, Kurdistan Region, Iraq.
Ahmed Hussein ZwamelMedical Laboratory Technique College, The Islamic University, Najaf, Iraq.
Ahmed HjaziDepartment of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Raghav VashishthDepartment of Surgery, National Institute of Medical Sciences, NIMS University Rajasthan, Jaipur, India.
Masoumeh BeigDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Methods: We conducted a comprehensive systematic search across four major scientific databases: Scopus, PubMed, Web of Science, and EMBASE, targeting articles published until December 13, 2023. This meta-analysis focused on studies that examined antibiotic resistance in GBS strains. The Joanna Briggs Institute tool was employed to assess the quality of the included studies. This meta-analysis applied a random-effects model to synthesize data on antibiotic resistance in GBS, incorporating subgroup analyses and regression techniques to explore heterogeneity and trends in resistance rates over time. Outliers and influential studies were identified using statistical methods such as Cook's distance, and funnel plot asymmetry was assessed to evaluate potential publication bias. All analyses were conducted using R software (version 4.2.1) and the metafor package (version 3.8.1). Results: This study included 266 studies from 57 countries, revealing significant variability in GBS antibiotic resistance rates. The highest resistance rates were observed for tetracycline (80.1, 95% CI: 77.1-82.8%), while tedizolid (0.1, 95% CI: 0.0-0.8%) showed the lowest resistance rates. Significant heterogeneity in resistance rates was observed, particularly for antibiotics such as azithromycin and gentamicin ( Conclusion: This study emphasizes the growing issue of antibiotic resistance in GBS strains. Notable resistance to older and newer antibiotics, increasing resistance over time, regional disparities, and methodological variations are noted. Rising resistance trends for multiple antibiotics underscore the urgent need for global surveillance and improved antibiotic stewardship. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024566269, CRD42024566269.

Indexed as

antibiotic resistanceantibiotic susceptibilitygroup B StreptococcusJoanna Briggs Institute toolmeta-analysis

Identifiers

PMID40342597
PMCPMC12060732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.