ArticleFrontiers in human neuroscience2025
Assessing prefrontal cortex activity in Graves' disease: a functional near-infrared spectroscopy study.
Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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7 authors.
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Abstract
Introduction: Graves' disease (GD) is associated with cognitive, emotional, and fatigue difficulties. Objective measures of cognitive dysfunction have yielded mixed results. The aim of this study was to investigated whether premenopausal female patients with first-time hyperthyroid GD (mean age 34 years) exhibit cognitive fatigability and altered functional activity in the prefrontal cortex (PFC) using functional near-infrared spectroscopy (fNIRS) during an exhausting cognitive task. Methods: Using the Animal Stroop test, we compared patients with GD ( Results: Both groups showed improvements in Stroop task performance after the reading task ( Discussion: In conclusion, we were not able to show any change in the functional activity of the PFC after prolonged mental activity in this set-up using fNIRS of hyperthyroid GD patients. Further studies are needed to understand the mechanism behind self-reported fatigue in GD.
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