Evidence map›Paper›PMID 40342524›Full record

ArticleJournal of biomedical optics2025

Evaluating blue light impact on reconstructed human epidermis using laser speckle imaging.

Léa Habib, Léa Abi Nassif, Marie Abboud, Rime Michael-Jubeli, Ali Tfayli, Roger Lteif

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Léa HabibUniversité Saint Joseph, Faculté des Sciences, Laboratoire d'étude cinétique en milieu hétérogène, Beirut, Lebanon.ORCID 0009-0004-3109-289X
Léa Abi NassifUniversité Saint Joseph, Faculté des sciences, Physics Department, UR TVA, Beirut, Lebanon.ORCID 0009-0000-4258-0427
Marie AbboudUniversité Saint Joseph, Faculté des sciences, Physics Department, UR TVA, Beirut, Lebanon.ORCID 0000-0002-7101-1001
Rime Michael-JubeliUniversité Paris-Saclay, Faculté de pharmacie, Unité Universitaire Interdisciplinaire Lip(Sys), Lipides, Systèmes analytiques et biologiques, Orsay, France.
Ali TfayliUniversité Paris-Saclay, Faculté de pharmacie, Unité Universitaire Interdisciplinaire Lip(Sys), Lipides, Systèmes analytiques et biologiques, Orsay, France.ORCID 0000-0002-9222-2852
Roger LteifUniversité Saint Joseph, Faculté des Sciences, Laboratoire d'étude cinétique en milieu hétérogène, Beirut, Lebanon.ORCID 0000-0002-0398-9411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Blue light exposure is ubiquitous in modern life, raising concerns about its potential impact on skin health. Aim: We aim to explore the effects of blue light on the reconstructed human epidermis (RHE) using the speckle analysis technique. Approach: RHE samples were irradiated with controlled doses of blue light (415 and 455 nm) at defined stages of their maturation. Following irradiation, speckle analysis was performed to assess the impact of blue light on the skin barrier. Results: Our results demonstrate that blue light irradiation significantly alters the scattering properties of RHE. Both wavelengths induced changes in the degree of linear polarization and speckle grain size, indicating disruptions in the skin barrier's structure and organization. The effects were found to be wavelength-dependent, with 455 nm irradiation showing more pronounced changes. Conclusions: Speckle imaging allowed detection of changes in the scattering properties of RHE. Findings suggest that blue light exposure can influence skin barrier function and may have implications for skin health and related conditions.

Indexed as

EpidermisLaser Speckle Contrast ImagingLightBlue LightHumansScattering, Radiationbarrier functionblue lightepidermal modelsreconstructed human epidermisspecklevisible light

Identifiers

PMID40342524
PMCPMC12058430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.