ArticleFrontiers in public health2025
Global, regional, and national burden of low back pain in working-age population from 1990 to 2021 and projections for 2050.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- 4-Week Comparative Outcomes of Standard Physiotherapy, Balneotherapy Plus Physiotherapy and Dextrose Prolotherapy in Patients with Low Back Pain: A Non-Randomized Study.Medicina (Kaunas, Lithuania) · 2026Trial
- Psoas Compartment Block Versus Medial Branch Block for Low Back Pain: A Narrative Review of Anatomical Targets, Clinical Evidence, and Patient Selection.Bioengineering (Basel, Switzerland) · 2026Review
- Artificial Intelligence for Clinical Decision Support in Rural Spine Care: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Chronic low back pain: assessment of mental distress, quality of life and pain-related activity patterns.Central European journal of public health · 2026Article
- Association Between Body Composition, Muscle-to-Weight Ratio, and Functional Disability in Patients with Chronic Non-Specific Low Back Pain: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Evolving Landscape of Regenerative Therapies: Cell-Based and Cell-Free Approaches for Chronic Low Back Pain.Journal of clinical medicine · 2026Review
- Utilization of an Ultrasonography-Computed Tomography Fusion System in the Lumbar Spine.International journal of spine surgery · 2026Article
- Differences in Depression and Anxiety, Quality of Life and Quality of Sleep Between Neuropathic and Nociceptive Patients with Chronic Low Back Pain: A Comparative, Multi-Center, Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Sex- and Age-Related Variation in Vertebral Geometry Influences Lumbar Spine Loading: An Image-Based Computational Modeling Study.Annals of biomedical engineering · 2026Article
- Low Back Pain in Chinese Adults Aged 45 Years and Older: Trends, Drivers, and Projections, 1990-2040.Healthcare (Basel, Switzerland) · 2026Article
- Static and Dynamic Motor Control in Active Young Adults: Associations with Oswestry Disability Index and Functional Movement Screen Asymmetries.Healthcare (Basel, Switzerland) · 2026Article
- Failed back surgery syndrome after non-instrumented lumbar surgery: Clinical report of a Tertiary care neurosurgical center.Pakistan journal of medical sciences · 2026Article
- A case series of two patients using closed-loop spinal cord stimulation: demonstration of the impact of real-time adjustments.Journal of surgical case reports · 2026Article
- Study on the effect of aquatic exercise combined with hot spring bathing for patients with chronic low back pain: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Metabolic Syndrome and Low Back Pain: Evidence from Cross-Sectional and Mendelian Randomization Analysis.Journal of pain research · 2026Article
- Lower chronic neck-back with higher planetary health diet adherence.Frontiers in nutrition · 2026Article
- Health-related quality of life among patients with low back pain attending rehabilitation facilities in Bangladesh: a cross-sectional study.BMJ public health · 2026Article
- Data Mining-Based Analysis of Acupoint Selection Patterns in Acupuncture Treatment for Lumbar Disc Herniation.Journal of pain research · 2026Review
- The risk factors of osteoporotic vertebral compression fracture accompanied with thoracolumbar fascial injury: a single-center retrospective study.Scientific reports · 2025Article
- Effect of training on knowledge, behaviors, and low back pain among marble workers: non-randomized experimental study.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Low back pain (LBP) is a leading cause of disability worldwide, especially among working-age group. This study evaluates the global, regional, and national burden of LBP among individuals aged 15-64 utilizing data from the Global Burden of Disease (GBD) 2021 study. Methods: We assessed trends in incidence, prevalence, and disability-adjusted life years (DALYs) for LBP from 1900 to 2021. Age-standardized rates (ASRs) were calculated, and joinpoint regression and decomposition analyses were used to identify key drivers. Future trends were projected through 2050. Results: The prevalence of LBP in working-age group has risen to 452.8 million cases globally, a 52.66% increase since 1990. South Asia reported the highest absolute number of cases, while Central and Eastern Europe showed the highest ASRs. Across all regions, women consistently exhibited higher incidence, prevalence, and DALYs than men. Decomposition analysis revealed that population growth was the main factor contributing to the rising burden. Projections indicate that LBP cases will continue increasing through 2050, particularly among women, although ASRs are expected to decline. Conclusion: The burden of LBP among working-age group is growing due to population expansion. Despite declining ASRs, substantial regional and gender disparities remain, highlighting the need for targeted public health strategies.
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