Evidence map›Paper›PMID 40342478›Full record

ArticleCureus2025

Possible Capecitabine-Induced Coronary Vasospasm and Myocardial Infarction.

Deepa Soodi, Vinod Kumar Reddy Cirra, Guruprasad D Naik, Param Sharma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deepa SoodiCardiology, Marshfield Clinic Health System, Marshfield, USA.
Vinod Kumar Reddy CirraInternal Medicine, Deccan College of Medical Sciences, Hyderabad, IND.
Guruprasad D NaikCardiology, Goa Medical College, Bambolim, IND.
Param SharmaCardiology, Marshfield Clinic Health System, Marshfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capecitabine is a 5-fluorouracil precursor, approved for breast and colorectal cancer. We report a case of capecitabine-induced coronary vasospasm. A 77-year-old woman with breast cancer receiving capecitabine presented with chest pain, and an electrocardiogram demonstrated acute anterior-lateral myocardial infarction. Coronary angiography demonstrated normal coronary arteries. Discontinuation of capecitabine resolved symptoms. Failing to identify the cardiotoxicity associated with capecitabine could have had serious consequences.

Indexed as

capecitabine side effectschemotherapy-related toxicitycoronary artery vasospasmmyocardial infarctionst-segment elevation myocardial infarction (stemi)

Identifiers

PMID40342478
PMCPMC12059612

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.