Evidence map›Paper›PMID 40342264›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2025

Hyaluronic Acid-Based Bleaching Gels With NF_TiO

Marcos Roberto de Lima de Benati, Priscila Borges Gobbo de Melo, Rafael Antonio de Oliveira Ribeiro, Fernando Luis Esteban Florez, Carlos Alberto de Souza Costa, Vanessa Cavalli

Abstract read
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Hyaluronic Acid-Based Bleaching Gels With NF_TiOJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcos Roberto de Lima de BenatiDepartment of Restorative Dentistry, University of Campinas-Piracicaba Dental School (FOP-UNICAMP), Piracicaba, SP, Brazil.ORCID 0000-0002-6289-8114
Priscila Borges Gobbo de MeloDepartment of Restorative Dentistry, University of Campinas-Piracicaba Dental School (FOP-UNICAMP), Piracicaba, SP, Brazil.ORCID 0000-0001-6482-3274
Rafael Antonio de Oliveira RibeiroDepartment of Physiology and Pathology, Araraquara School of Dentistry (FOAr/UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0001-8100-3294
Fernando Luis Esteban FlorezDepartment of Restorative Sciences, University of Oklahoma-Health Sciences Center, Oklahoma City, Oklahoma, USA.
Carlos Alberto de Souza CostaDepartment of Physiology and Pathology, Araraquara School of Dentistry (FOAr/UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0002-7455-6867
Vanessa CavalliDepartment of Restorative Dentistry, University of Campinas-Piracicaba Dental School (FOP-UNICAMP), Piracicaba, SP, Brazil.ORCID 0000-0002-9459-1926

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 001São Paulo Research Foundation (FAPESP) 2022/04618-8;20/06782-4
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and cytotoxicity of in-office bleaching gels with hyaluronic acid (HA) or carbomer 940 (CAR), titanium dioxide nanoparticles co-doped with nitrogen and fluorine (NF_TiO MATERIALS AND

methods48 bovine enamel/dentin discs (5 × 3 mm) stained with black tea for 24 h were assigned to six groups (n = 8): HA-1.5%HP + LED, HA-6%HP + LED, CAR-1.5%HP + LED, CAR-6%HP + LED, 35%HP-commercial (control), and a negative control (no treatment). The discs were placed in artificial pulp chambers (APCs) and underwent three 30-min bleaching sessions with 20 violet LED cycles (1-min activation, 30-s pause) at 7-day intervals. Extracts were applied to MDPC-23 cells, assessing color change (ΔE

resultsGels with HA showed no statistical difference in ΔE

conclusionBleaching gels with HA, NF_TiO CLINICAL RELEVANCE: Experimental bleaching gels with hyaluronic acid, NF_TiO

Indexed as

Hyaluronic AcidHydrogen PeroxideTitaniumTooth BleachingTooth Bleaching AgentsAnimalsCattleCell SurvivalGelsGelsHyaluronic AcidHydrogen PeroxideTitaniumtitanium dioxideTooth Bleaching Agentsdental bleachinghyaluronic acidhydrogen peroxidenanotechnologytitanium

Identifiers

PMID40342264
PMCPMC12315631

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.