ArticleInterdisciplinary cardiovascular and thoracic surgery2025
Association between aortic low-attenuation plaques and the risk of cerebral infarction in hybrid aortic arch repair.
Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- CT-Derived Aortic Plaque Characteristics Predict MRI-Detected Silent Cerebral Infarction after Total Aortic Arch Replacement.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the association between aortic low-attenuation plaque (LAP) and the risk of cerebral infarctions, including microemboli, during hybrid aortic arch repair.
methodsBetween January 2016 and February 2023, 149 patients underwent hybrid aortic arch repair. Patients were excluded if they lacked preoperative or postoperative magnetic resonance imaging (MRI), had insufficient computed tomography (CT) data, a history of arch replacement or Kommerell's diverticulum. The LAP area (CT values: 0-60 Hounsfield unit) was measured in the total and the greater curvature area of aorta. The LAP area was categorized as large or small based on the median value. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for new cerebral infarction lesions (NCILs).
resultsEighty-four patients were evaluated for NCILs using both pre- and postoperative MRI (NCIL positive: 41 patients, NCIL negative: 43 patients). The NCIL-positive group had a higher proportion of zone 0 landing (46% versus 21%; P = 0.020), greater use of the chimney graft technique (20% versus 5%; P = 0.046) and a larger LAP area in the greater curvature of the aortic arch (27 mm2 versus 13 mm2; P < 0.001). Multivariable-adjusted logistic regression model showed a large LAP area in the greater curvature of the aortic arch significantly increased the risk of NCILs (OR 5.23, 95% CI 1.29-18.34).
conclusionsA large LAP area in the greater curvature of the aortic arch is independently associated with an increased risk of NCILs during hybrid aortic arch repair.
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