Evidence map›Paper›PMID 40341935›Full record

ArticleDiscover mental health2025

Functional brain changes related to adverse childhood experiences and the presence of psychopathology.

Sophia Laney, Kate Nooner

Abstract read
In one paragraph

Article in Discover mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophia LaneyDepartment of Psychology, University of North Carolina Wilmington (UNCW), 601 South College Rd, Box 5612, Wilmington, NC, 28403-5612, USA.
Kate NoonerDepartment of Psychology, University of North Carolina Wilmington (UNCW), 601 South College Rd, Box 5612, Wilmington, NC, 28403-5612, USA. noonerk@uncw.edu.

Funding

Biomarkers of Underage Binge Drinking in Maltreated ChildrenR15AA023251 · NIAAA · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI NOONER, KATE BRODY · 2016 to 2016
$440k
Biomarkers of Binge Drinking in Maltreated AdolescentsR15AA028911 · NIAAA · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI NOONER, KATE BRODY · 2022 to 2022
$380k
NIAAA NIH HHS R15 AA023251NIAAA NIH HHS R15 AA028911NIAAA NIH HHS R15 AA028911 & R15 AA023251
6 · The paper itself

Abstract

Research suggests that associated changes in brain function may underlie the vulnerabilities for psychopathology following adverse childhood experiences (ACEs). In addition to the ACEs themselves, the development of trauma symptoms following ACEs may also contribute to psychopathology. The present study investigates how exposure to certain ACEs, specifically child maltreatment, and trauma symptoms both individually and combined, influence the presence of psychopathology in a sample of adolescents. Participants were 52 adolescents between the ages of 12-14 years recruited from New Hanover County Health and Human Services (NHC-HHS). Further, this study seeks to identify functional brain changes with electroencephalography (EEG) that may impact psychopathology in youth. While child maltreatment and trauma symptoms were not associated, results indicated that frontal and central EEG alpha power, but not alpha asymmetry, were associated with an increased likelihood of experiencing psychopathology in adolescents, with higher alpha power reflecting lower cortical activation. The results of this study suggest that certain changes in patterns of neural activity may be candidates for psychopathology prevention in adolescents.

Indexed as

Adverse childhood experiences (ACEs)Brain functionChild maltreatmentEEGPsychopathologyTrauma

Identifiers

PMID40341935
PMCPMC12061819

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.