Evidence map›Paper›PMID 40341914›Full record

ArticleJournal of burn care & research : official publication of the American Burn Association2025

A Proof-of-Concept for a Continuous-Temperature Circulating Water Bath in Frostbite Limb Rewarming.

Robert McKenzie, Zoë Anderson, Sebastian Kilcommons, Joshua N Wong, Alexis Armour

Abstract read
In one paragraph

Article in Journal of burn care & research : official publication of the American Burn Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synthesis of Protocols for Frostbite Care From the FROST Study Sites.Journal of burn care & research : official publication of the American Burn Association · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert McKenzieFaculty of Medicine and Dentistry, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Zoë AndersonFaculty of Medicine and Dentistry, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Sebastian KilcommonsFaculty of Medicine and Dentistry, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Joshua N WongFaculty of Medicine and Dentistry, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Alexis ArmourFaculty of Medicine and Dentistry, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.ORCID 0009-0009-3904-2164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frostbite is a thermal tissue injury that can occur following prolonged exposure to freezing temperatures, often resulting in tissue ischemia and sometimes requiring amputation. The American Burn Association recommends rapid rewarming of frostbite injuries in 38-42 °C water for 15-30 minutes, but clinical application of this recommendation is often inconsistent. Our objective was to find a method to better facilitate frostbite treatment by creating a continuous-temperature circulating water bath and demonstrating its effectiveness with a proof-of-concept, descriptive study. We hypothesized that this design would effectively rewarm chilled extremities within 30 minutes without healthcare workers being required to continually monitor and maintain water temperature. We constructed a continuous-temperature circulating water bath system using a reservoir and an Anova Precision Cooker NANO. Pig feet were chilled and then immersed in 39.0 °C water with or without the Anova Precision Cooker NANO. Without the Anova Precision Cooker NANO, tissue warmed from 3.2 ± 0.3 °C to 34.2 ± 0.2 °C over 30 minutes (final water temperature of 36.5 ± 0.1 °C). With it, tissue warmed from 2.7 ± 0.2 °C to 36.7 ± 0.2 °C (final water temperature of 39.1 ± 0.1 °C). The continuous-temperature circulating water bath offers a standardized, reliable, and effective method for rewarming hypothermic tissue. Our approach could provide a solution to inconsistent and impractical frostbite rewarming methods in clinical settings to better promote rewarming compliance. Further studies are ongoing to validate the feasibility of using the continuous-temperature circulating water bath in clinical practice.

Indexed as

FrostbiteRewarmingAnimalsProof of Concept StudySwinefreezing cold injuryfrostbite injuryfrostbite rewarmingfrostbite treatment

Identifiers

PMID40341914
PMCPMC12596580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.