Evidence map›Paper›PMID 40341820›Full record

ArticleJournal of digestive diseases

The Role of Endoscopic Grading of Gastric Intestinal Metaplasia (EGGIM) in Assessing the Extent and Degree of Gastric Intestinal Metaplasia.

Dong Lyu, Jing Zhao, Hai Feng Jin, Bin Lyu

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Article in Journal of digestive diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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  3. Impact ofAnnals of gastroenterology
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Dong LyuDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.ORCID https://orcid.org/0009-0003-7897-1368
Jing ZhaoDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.
Hai Feng JinDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.ORCID https://orcid.org/0000-0001-8357-9377
Bin LyuDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.ORCID https://orcid.org/0000-0002-6247-571X

Funding

"Pioneer" and "Leading Goose" R&D Program of Zhejiang Province 2023C03050
6 · The paper itself

Abstract

objectivesWe aimed to evaluate the consistency between endoscopic grading of gastric intestinal metaplasia (EGGIM) and the operative link on gastric intestinal metaplasia assessment (OLGIM) staging, as well as the value of endoscopic grading of gastric intestinal metaplasia (GIM) in early gastric cancer (EGC) risk.

methodsThe sample size was estimated to be at least 210 patients. To evaluate GIM, EGGIM staging was used during magnifying endoscopy with narrow-band imaging, while the OLGIM staging was carried out according to the updated Sydney system. The consistency between the two scoring systems and the accuracy of EGGIM in diagnosing OLGIM III/IV cases were evaluated. EGC risk was evaluated using the Kimura-Takemoto classification, the operative link on gastritis assessment (OLGA)/OLGIM, and EGGIM.

resultsAmong the 210 patients, 68 (32.4%) had (previous) EGC and 142 (67.6%) had chronic atrophic gastritis (CAG). EGGIM and OLGIM staging showed good consistency (κ = 0.805, U = 12.620, p < 0.001) in diagnosing OLGIM III/IV GIM, with an area under the receiver operating characteristic curve for EGGIM of 0.95. Using a cut-off value of > 4, the sensitivity and specificity were 95.7% and 91.4%, respectively. The EGGIM score was higher in the EGC group than in the CAG group (4.93 vs. 3.92, p < 0.001).

conclusionsEGGIM shows good diagnostic performance and consistency with OLGIM, which can simplify endoscopic surveillance by reducing the need for biopsy. The EGGIM score is associated with EGC risk, and endoscopic surveillance is recommended for patients with EGGIM score > 4.

Indexed as

Gastric MucosaGastroscopyPrecancerous ConditionsStomachStomach NeoplasmsAdultAgedFemaleGastritis, AtrophicHumansMaleMetaplasiaMiddle AgedNarrow Band Imagingatrophic gastritisearly gastric cancerendoscopic grading of gastric intestinal metaplasiagastric intestinal metaplasiaoperative link on gastric intestinal metaplasia assessment

Identifiers

PMID40341820
PMCPMC12198661

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.