Evidence map›Paper›PMID 40341759›Full record

ArticleScientific reports2025

Reconstruction of the X and Y haplotypes in the genetically improved Abbassa nile tilapia genome assembly.

Graham Etherington, Adam Ciezarek, Tarang Mehta, Tom Barker, Alex Durrant, Fiona Fraser, Suzanne Henderson, Naomi Irish, Gemy Kaithakottil, Vanda Knitlhoffer and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Graham Etherington *Earlham Institute, Norwich Research Park, Norwich, UK.
Adam Ciezarek *Earlham Institute, Norwich Research Park, Norwich, UK.
Tarang Mehta *Earlham Institute, Norwich Research Park, Norwich, UK.
Tom BarkerEarlham Institute, Norwich Research Park, Norwich, UK.
Alex DurrantEarlham Institute, Norwich Research Park, Norwich, UK.
Fiona FraserEarlham Institute, Norwich Research Park, Norwich, UK.
Suzanne HendersonEarlham Institute, Norwich Research Park, Norwich, UK.
Naomi IrishEarlham Institute, Norwich Research Park, Norwich, UK.
Gemy KaithakottilEarlham Institute, Norwich Research Park, Norwich, UK.
Vanda KnitlhofferEarlham Institute, Norwich Research Park, Norwich, UK.
Shimaa AliWorldFish, Abbassa, Abou-Hammad, Sharkia, Egypt.
Trinh TrongWorldFish, Jalan Batu Maung, Penang, Malaysia.
Chris WatkinsEarlham Institute, Norwich Research Park, Norwich, UK.
David SwarbreckEarlham Institute, Norwich Research Park, Norwich, UK.
Karim GharbiEarlham Institute, Norwich Research Park, Norwich, UK.
John BenzieWorldFish, Jalan Batu Maung, Penang, Malaysia. Benzie@cgiar.org.
Wilfried HaertyEarlham Institute, Norwich Research Park, Norwich, UK. wilfried.haerty@earlham.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/CCG1720/1Biotechnology and Biological Sciences Research Council BB/CSP1720/1Consortium of International Agricultural Research Centers Program on Fish Agri-Food Systems
6 · The paper itself

Abstract

The success of the Nile tilapia (Oreochromis niloticus) as an aquaculture species is partly the result of continuous selective breeding leading to high performing strains. These elite strains have been derived from breeding populations of diverse origins and crosses with other Oreochromis species. Owing to the complex and unique evolutionary histories of each strain, existing reference genomes of wild populations are unsuitable to implement genomic selection for beneficial traits such as growth or environmental resilience in aquaculture programmes. Here we generated a high-quality genome assembly and annotation of the WorldFish Genetically Improved Abbassa Nile tilapia (GIANT) elite strain using a combination of PacBio HiFi, and Omni-C Illumina sequencing. As a male Abbassa Nile tilapia was used for the generation of the genome assembly, we reconstructed both X and Y haplotypes, identifying both amhY and amhΔy on LG23 indicating that Abbassa likely shares the same sex determination system as GIFT, and thereby differs from the existing reference genome, whose sex determination loci are located on LG1.

Indexed as

CichlidsGenomeHaplotypesX ChromosomeY ChromosomeAnimalsFemaleMaleAbbassaGenome assemblyIntrogressionNile tilapiaOreochromis niloticusSex determination

Identifiers

PMID40341759
PMCPMC12062369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.