ReviewDiscover oncology2025
A bibliometric analysis of nucleic acid probe and its applications in oncology: towards more precise molecular medicine.
Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNucleic acid probes, which are short sequences of nucleic acids designed to complement specific DNA or RNA targets, have broad applications in biosensing, genetic studies, and various other fields. In tumor diagnosis and treatment, nucleic acid probes offer a precise and accessible approach that is essential for improving patient care and quality of life. Despite substantial research on nucleic acid probes over the past three decades, few comprehensive reviews have retrospectively examined the field.
methodsThis study extracted 30 years of nucleic acid probe-related research articles from the Web of Science Core Collection database. We used CiteSpace, VOSviewer, and R tools to systematically analyze the field's current status and developmental trends, with an emphasis on applications in oncology.
resultsOur findings indicate a continuous growth trend in nucleic acid probe research, with the United States and China, along with their leading institutions and authors, making the most significant contributions. In oncology specifically, nucleic acid probe research has focused primarily on signal amplification, liquid biopsy, and drug delivery. The emergence of novel biomarkers and assay techniques has been a pivotal factor driving advancements in this field.
conclusionNucleic acid probes show strong potential for applications in tumor precise diagnosis and treatment. Continued innovation and closer interdisciplinary collaboration will be vital for further advancements, while large-scale clinical studies are needed to validate their clinical utility.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.