Evidence map›Paper›PMID 40341511›Full record

ArticleCurrent topics in behavioral neurosciences2025

A Personal and Scientific Introduction to the Work of A.D. (Bud) Craig on Interoception and the Insular Cortex.

Irina A Strigo, Alan N Simmons, Marc Wittmann

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Article in Current topics in behavioral neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irina A StrigoVeterans Affairs & University of California, San Francisco, San Francisco, CA, USA. irina.strigo@ucsf.edu.ORCID https://orcid.org/0000-0002-8799-716X
Alan N SimmonsVeterans Affairs & University of California, San Diego, San Diego, CA, USA. ansimmons@health.ucsd.edu.ORCID https://orcid.org/0000-0003-3963-2112
Marc WittmannInstitute for Frontier Areas of Psychology and Mental Health, Freiburg, Germany. wittmann@igpp.de.ORCID https://orcid.org/0000-0002-4483-7334

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A.D. (Bud) Craig was best known to us colloquially as Bud Craig; his groundbreaking work has advanced our understanding of the neuroanatomical basis of the bodily self, emotion, and subjective time. His research elucidated the intricate pathways of interoception - the brain's processing of internal body signals - and highlighted the insula's pivotal role in integrating these signals. Craig's pioneering insights demonstrated that bodily sensations, such as pain and temperature, are deeply intertwined with emotional experiences and homeostatic needs. By mapping the thalamocortical pathways and emphasizing the insula's function in predicting future bodily states, he provided a comprehensive framework that connects physiological states to emotional and temporal experiences. This fundamental work has profoundly influenced a new generation of scientists and inspired the current volume. In this book, we have invited researchers influenced by Craig's theories to explore the neural correlates of emotion, pain, interoception, and time. In this chapter, we present how the editors of this book were directly influenced by Craig's findings and lay the groundwork for the large collective contribution of the authors of the subsequent chapters that continue to explore this ever-evolving scientific landscape.

Indexed as

Cerebral CortexInsular CortexInteroceptionEmotionsHistory, 20th CenturyHumansEmotionsInsulaInteroceptionPainTime perception

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.