Observational studyJournal of general internal medicine2025
Perceived Companionship Is Associated with Pain Severity but Not Opioid Tapering Among Veterans with Chronic Pain.
Observational study in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundChronic pain is more prevalent among Veterans than in the general population, and greater social support is linked to better pain outcomes and emotional well-being. For Veterans with chronic pain, social connections can enhance treatment effectiveness, while for those on long-term opioid therapy (LTOT), support may also facilitate pain management and opioid tapering.
objectiveTo explore the relationship between self-reported companionship and changes in pain and opioid dosage among Veterans with chronic pain prescribed LTOT.
designProspective observational cohort study of primary care patients prescribed LTOT in the Veterans Health Administration
participantsA total of 290 Veterans prescribed LTOT MAIN MEASURES: Self-reported companionship was assessed using the 4-item PROMIS Companionship measure at 18-month follow-up, and cohorts were dichotomized into high (N=156) and low (N=134) companionship groups. We assessed pain severity and pain interference with the 3-item PEG scale along with multiple secondary measures, with up to 18 months of follow-up.
resultsPEG scores were significantly lower in the high companionship group (6.5, 6.5, 6.3 at baseline, 12 months, and 18 months, respectively) compared to the low companionship group (7.3, 7.4, 7.1 at baseline, 12 months, and 18 months, respectively, p<0.001 in each case). High and low companionship groups did not differ significantly in mean opioid dose at any time point, nor did they differ in opioid daily dose change over time or whether dose tapering was voluntary or involuntary. High companionship was associated with significantly better general health status, less depression/anxiety, less fatigue, and better pain self-efficacy, but was not associated with sleep.
conclusionsWe found that high perceived companionship was associated with lower pain severity in Veterans with chronic pain on LTOT. However, changes in opioid medication dosage were not related to companionship levels. Findings suggest that approaches to enhancing companionship could be an important strategy in management of chronic pain.
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