Evidence map›Paper›PMID 40341400›Full record

SynthesisScientific reports2025

Disease burden of rotavirus related diarrhea in children under 5 years in China: a meta-analysis.

Li Cai, Bicheng Tang, Fanxu Kong, Zhaorui Chang, Yanping Zhang, Yaming Zheng, Liping Wang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li CaiDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Bicheng TangThe Sixth People's Hospital of Dongguan, Dongguan, 523129, Guangdong, China.
Fanxu KongDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Zhaorui ChangDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Yanping ZhangDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.
Yaming ZhengDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. zhengym@chinacdc.cn.
Liping WangDivision of Infectious Disease, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, 102206, China. wanglp@chinacdc.cn.

Funding

Beijing Natural Science Foundation L232011
6 · The paper itself

Abstract

Rotavirus (RV) is a leading cause of severe diarrhea among children under five years of age in China. In this meta-analysis, we assessed the disease burden of RV-related diarrhea by analyzing 73 studies retrieved from the PubMed, Web of Science, China National Knowledge Infrastructure, and Wanfang databases (2013-2023). The incidence of RV-related diarrhea ranged from 0.637 /1000 to 31.46/1000 persons. The pooled RV positivity rate for the under-5 age group was 24.7% (95% confidence interval: 22.1-27.4), with higher positivity rates observed among inpatients compared to outpatients (24.1% vs. 22.2%). Notably, the RV positivity rate declined from 27.3 to 21.5% pre- and post- the RotaTeq

Indexed as

Cost of IllnessDiarrheaRotavirusRotavirus InfectionsChild, PreschoolChinaCOVID-19GenotypeHumansIncidenceInfantInfant, Newborn

Identifiers

PMID40341400
PMCPMC12062226

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.