Evidence map›Paper›PMID 40341309›Full record

ArticleGenetics and molecular biology2025

Fecal Virome of Southeastern Maned Sloth (Bradypus crinitus) (Pilosa: Bradypodidae).

Amanda Coimbra, Mirela D'arc, Filipe Romero Rebello Moreira, Matheus Augusto Calvano Cosentino, Francine Bittencourt Schiffler, Thamiris Dos Santos Miranda, Ricardo Mouta, Déa Luiza Girardi, Victor Wanderkoke, Gabriel Medeiros and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Amanda CoimbraUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Mirela D'arcUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Filipe Romero Rebello MoreiraUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Matheus Augusto Calvano CosentinoUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Francine Bittencourt SchifflerUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Thamiris Dos Santos MirandaUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Ricardo MoutaUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Déa Luiza GirardiUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Victor WanderkokeUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Gabriel MedeirosUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
Talitha Mayumi FranciscoUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Laboratório de Ciências Ambientais, Campos dos Goytacazes, RJ, Brazil.
Flávio Landim SoffiatiUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Laboratório de Ciências Ambientais, Campos dos Goytacazes, RJ, Brazil.
Suelen Sanches FerreiraUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Laboratório de Ciências Ambientais, Campos dos Goytacazes, RJ, Brazil.
Carlos Ramon Ruiz-MirandaUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Laboratório de Ciências Ambientais, Campos dos Goytacazes, RJ, Brazil.
Marcelo Alves SoaresUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.
André Felipe Dos SantosUniversidade Federal do Rio de Janeiro (UFRJ), Laboratório de Diversidade e Doenças Virais, Rio de Janeiro, RJ, Brazil.ORCID 0000-0003-3372-1552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a viral metagenomic analysis of fecal samples from Bradypus crinitus (Pilosa: Bradypodidae), a recently described sloth species that occurs in the Atlantic Forest of Espírito Santo and Rio de Janeiro states, Southeast Brazil. Through Illumina sequencing, we generated a total of 2,065,344 raw reads, of which 945,386 reads (45.77%) passed the quality and size filter. The highest proportion of them was assigned to Eukarya, followed by Bacteria and only a small proportion to Virus. However, we identified 24 viral families using distinct taxonomic assignment tools, including phages and vertebrate viruses, such as retroviruses and papillomaviruses. Also, we identified four bacterial genus already associated with disease in sloths. Our study sheds light on the microbiome of a previously unexplored species, further contributing to the comprehension of metagenomic global diversity.

Identifiers

PMID40341309
PMCPMC12063671

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.