Evidence map›Paper›PMID 40341218›Full record

ArticleInternational journal of impotence research2026

Traditional and individual care pathways in gender-affirming healthcare for transgender and gender-diverse individuals - results from the ENIGI follow-up study.

Andreas Koehler, Inga Becker-Hebly, Els Elaut, Baudewijntje Kreukels, Peer Briken, Gunter Heylens, Thomas D Steensma, Timo Nieder

Abstract readMulticenter Study
In one paragraph

Article in International journal of impotence research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andreas KoehlerInstitute for Sex Research, Sexual Medicine, and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. an.koehler@uke.de.ORCID http://orcid.org/0000-0003-0415-3007
Inga Becker-HeblyInstitute for Sex Research, Sexual Medicine, and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Els ElautCenter of Sexology and Gender, University Hospital Ghent, Ghent, Belgium.ORCID http://orcid.org/0000-0002-5295-2009
Baudewijntje KreukelsDepartment of Medical Psychology, The Center of Expertise on Gender Dysphoria Amsterdam, VU University Medical Center Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-9713-4835
Peer BrikenInstitute for Sex Research, Sexual Medicine, and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gunter HeylensCenter of Sexology and Gender, University Hospital Ghent, Ghent, Belgium.
Thomas D SteensmaDepartment of Medical Psychology, The Center of Expertise on Gender Dysphoria Amsterdam, VU University Medical Center Amsterdam, Amsterdam, the Netherlands.
Timo NiederInstitute for Sex Research, Sexual Medicine, and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment requests in transgender healthcare are heterogenous and not all transgender and gender-diverse individuals want to undergo the various transition-related medical interventions offered. This study aims to explore demographic and treatment-related predictors associated with different transgender care pathways in a multicenter, multinational clinical setting. In this follow-up study, 539 adult participants from Belgium, Germany, and the Netherlands took part and were categorized as following a 'traditional' care pathway (i.e., undergoing all transition-related interventions), an 'individual' care pathway (i.e. any course of treatment deviating from the traditional pathway), or 'no care' pathway (i.e. not seeking transition-related medical interventions.). We analyzed differences in demographic (e.g., gender identity) and clinical variables (e.g., treatment satisfaction), conducting logistic regression analysis and descriptive subgroup analysis. Participants with a non-binary gender were 6.7 times more likely to follow an individual care pathway, while participants with higher treatment satisfaction were less likely to follow an individual care pathway (Odds Ratio: 0.6). We identified four patterns of individual transgender care pathways, some as a function of the sex assigned at birth. The present study provides valuable insights into demographic and treatment-related predictors associated with different transgender care pathways. Healthcare providers should be aware of individual transgender care pathways and the association with (non)-binary genders to provide tailored transgender healthcare and ensure individualized, high-quality service provision.

Indexed as

Critical PathwaysGender-Affirming ProceduresTransgender PersonsAdultBelgiumDelivery of Health CareFemaleFollow-Up StudiesGender-Affirming CareGender IdentityGermanyHumansMaleMiddle AgedNetherlandsPatient Satisfaction

Identifiers

PMID40341218
PMCPMC12864032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.