Trial reportScientific reports2025
Split-belt treadmill training improves gait symmetry and lower limb function in patients with stroke.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07057700 (Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
Who cites it
5 citing papers in PubMed.
- Recent research on rehabilitation interventions for post-stroke gait and balance in low- and middle-income countries: a scoping review.BMC health services research · 2026Article
- Locomotor adaptation on a split-belt treadmill: mechanisms, modulation, and clinical utility.Journal of neurophysiology · 2026Review
- A novel scheme for speed variation of a robotic cane to improve step length symmetry during overground walking.Scientific reports · 2025Article
- A model of the cerebellum generates gait adaptations in a reflex-based neuromusculoskeletal model during split-belt walking.Journal of neuroengineering and rehabilitation · 2025Article
- A model of the cerebellum generates gait adaptations in a reflex-based neuromusculoskeletal model during split-belt walking.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Split-belt treadmill training (SBTT) enhances gait symmetry in patients with stroke (PwS) by improving sensorimotor adaptation, However, it remains unclear whether repeated SBTT leads to long-term acquisition of gait adaptation skills and whether it improves functional walking in PwS. This study aimed to investigate the effect of SBTT on gait symmetry and lower limb function in PwS. We designed a parallel-group randomized controlled experiment. PwS who have the ability to stand and walk unassisted for at least 30 min were included in this study. They were randomly assigned to either rehabilitation with SBTT or with tied-belt treadmill training (TBTT). The treatment was provided once per day, five times per week for four weeks(total of 20 treatments). Gait analysis including step length, gait speed, temporal and spatial asymmetry and clinical assessment of lower limb function using Fugl-Meyer Assessment - lower extremity (LEFM), the Berg Balance Scale (BBS), the Wisconsin Gait Scale(WGS), and the Timed Up and Go Test (TUGT) were measured at baseline, 2 weeks post intervention, 4 weeks post intervention, and at follow-up after 4 weeks finishing the exercise. Two-way repeated measures ANOVA was used for intergroup comparisons between the two groups at different time points. In addition, Pearson correlation analysis was used to test the relationship between the improvement of clinical assessment scales and changes in gait parameters. Results showed that SBTT could effectively and efficiently improve the spatial asymmetry and speed of gait, as well as lower limb balance and walking function in PwS. In addition, the improvement of functional walking was positively correlated with the decrease of spatial asymmetry, and the increase of step length of paretic leg. In Conclusion, a 4-week SBTT intervention could effectively improve gait asymmetry and, consequently, enhance walking and lower limb function in PwS with independent walking ability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.