ReviewMolecular horticulture2025
ORANGE family proteins: multifunctional chaperones shaping plant carotenoid level, plastid development, stress tolerance, and more.
Review in Molecular horticulture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Focus on DnaJ protein research from Arabidopsis to crop improvement.The plant genome · 2026Review
- ORANGE: a tale of two pigments and two organelles.Plant cell reports · 2026Review
- Regulation of chloroplast biogenesis and differentiation.Journal of experimental botany · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
ORANGE (OR) family proteins are DnaJE1 molecular chaperones ubiquitous and highly conserved in all plant species, indicating their important roles in plant growth and development. OR proteins have been found to exert multiple functions in regulating carotenoid and chlorophyll biosynthesis, plastid development, and stress tolerance, with additional functions expected to be discovered. As molecular chaperones, OR proteins directly influence the stability of their target proteins via their holdase activity and may perform other molecular roles through unknown mechanisms. Exploration of OR has uncovered novel mechanisms underlying core plant metabolism pathways and expanded our understanding of processes linked to plastid development. Continued investigation of OR family proteins will not only reveal new functions of molecular chaperones but also provide pioneering tools for crop improvement. Thus, OR family proteins offer a distinctive opportunity to comprehend molecular chaperones in modulating various metabolic and developmental processes and exemplify the importance of chaperones in crop development and adaptability. This review briefly details the history of OR family proteins, highlights recent advancements in understanding their myriad of functions, and discusses the prospects of this fascinating group of chaperones towards generating innovative, more nutritious, and resilient crops alongside other agronomically important traits.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.