Evidence map›Paper›PMID 40341090›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

First-in-Human Study of

Sadamitsu Ichijo, Tetsu Arisawa, Mai Hatano, Waki Nakajima, Tomoyuki Miyazaki, Tsuyoshi Eiro, Yuuki Takada, Ryunosuke Iai, Akane Sano, Masaki Sonoda and 3 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. "Pseudo-reference-based Input Function Shape" (pRef-IFS): Towards a True image-derived input function for PET kinetic modeling.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sadamitsu IchijoDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tetsu ArisawaDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Mai HatanoDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Waki NakajimaDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tomoyuki MiyazakiDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Tsuyoshi EiroDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Yuuki TakadaDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Ryunosuke IaiDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Akane SanoDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Masaki SonodaDepartment of Neurosurgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan; and.
Yutaro TakayamaDepartment of Neurosurgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan; and.
Yuichi KimuraFaculty of Informatics, Cyber Informatics Institute, Kindai University, Higashi-Osaka, Japan.
Takuya TakahashiDepartment of Physiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan; takahast@yokohama-cu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the alteration of glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) distribution is believed to underlie physiologic and pathologic neuronal function, there has been no modality to evaluate AMPARs in a living human. [

Indexed as

Fluorine RadioisotopesPositron-Emission TomographyRadiopharmaceuticalsReceptors, AMPAAdultBrainCarbon RadioisotopesFemaleHumansMaleMiddle AgedRadioactive TracersTissue DistributionYoung AdultCarbon RadioisotopesFluorine-18Fluorine RadioisotopesRadioactive TracersRadiopharmaceuticalsReceptors, AMPAAMPA receptorfirst-in-human studyneuroimagingPET

Identifiers

PMID40341090
PMCPMC12175988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.