Evidence map›Paper›PMID 40341071›Full record

ReviewJournal of cardiothoracic surgery2025

Presentation of a residual post-myocardial infarction ventricular septal defect; a literature review based on a case report.

Mehrdad Jafari, Mohammad Khani, Tooba Akbari, Elham Farahani, Fariba Bayat, Abdulhamid Bagheri, Amir Nasrollahizadeh, Pedram Ramezani, Pouya Ebrahimi, Mohammad Hossein Mandegar

Abstract readCase ReportsReview
In one paragraph

Review in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mehrdad JafariCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad KhaniCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tooba AkbariCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Elham FarahaniCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. farahani13025@gmail.com.
Fariba BayatCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abdulhamid BagheriCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amir NasrollahizadehTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Pedram RamezaniFaculty of Medicine, Azad University of Medical Sciences, Tehran, Iran.
Pouya EbrahimiTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein MandegarDepartment of Cardiovascular Surgery, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the era of modern techniques for the early diagnosis and revascularization of myocardial infarction, post-myocardial infarction ventricular septal defect is rarely seen. However, this potentially fatal complication of ischemic cardiac events cannot always be detected and diagnosed in a straightforward pattern of practice. This study presents an initially delayed-presented post-infarction ventricular septal defect. CASE PRESENTATION: The patient was a 58-year-old white man who presented to the cardiology clinic complaining of moderate exertional dyspnea initiated two months ago and exacerbated by the time. His medical history includes an admission three years prior, where he was diagnosed with COVID-19 pneumonia and a myocardial infarction that was complicated by a ventricular septal defect (VSD) and hemodynamic instability. This condition was managed through urgent surgical revascularization and closure of the defect. Due to his current symptoms, further cardiac investigations were planned. A transthoracic echocardiogram was recommended after detecting a grade 3/6 systolic murmur during the physical examination. The initial assessment using an apical four-chamber TTE appeared normal. However, when performing a modified view with a posterior tilt, a bulging septum was observed, leaning toward the right ventricle. This bulging contained a defect with a left-to-right shunt, identified as a residual defect in the area of the repaired patch, along with a myocardial aneurysm. Due to the inconsequential findings from the echocardiogram study, the patient was scheduled for a follow-up echocardiogram, which showed no changes after six months. Additionally, the patient underwent therapeutic management addressing chronic obstructive pulmonary disease.

conclusionAlthough post-infarction ventricular septal defects are rarely seen in the revascularization era, the COVID-19 era was associated with an increase in the prevalence of this complication. It is important to be vigilant for patients who experienced an index event during that time. This potentially fatal complication can present with new issues following the initial event, such as residual defects. Comprehensive imaging studies are necessary to detect the underlying pathology. KEY CLINICAL MESSAGE: Diagnosing post-infarction ventricular septal defect requires the hypervigilance and precision of the cardiologist, who examines the patient and performs the cardiac imaging. Therefore, comprehensive investigations are crucial in patients with a suspicious history of ischemic cardiac events.

Indexed as

Heart Septal Defects, VentricularMyocardial InfarctionCOVID-19EchocardiographyHumansMaleMiddle AgedSARS-CoV-2Cardiac surgeryCase reportEchocardiogramMyocardial infarctionVentricular septal defect

Identifiers

PMID40341071
PMCPMC12063459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.