ArticleKnee surgery & related research2025
Thromboembolic and infectious complication risks in TKA and UKA: evidence from a Japanese nationwide cohort.
Article in Knee surgery & related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of perioperative glucocorticoids on glycemic control, PONV, and acute pain after primary bilateral total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2025Pooled it
- Optimizing resistance training for pain management in knee and hip osteoarthritis: a pairwise and dose-response meta-analysis.Frontiers in public health · 2025Pooled it
- Impact of cognitive impairment on postoperative delirium and discharge disposition following knee arthroplasty: a Japanese nationwide propensity score-matched study.Archives of orthopaedic and trauma surgery · 2026Article
- Age-stratified risk of major systemic complications following unicompartmental versus total knee arthroplasty: a nationwide cohort study.Knee surgery & related research · 2026Article
- Cerebrovascular disease and postoperative cognitive-related complications after knee arthroplasty: evidence from a nationwide cohort.Knee surgery & related research · 2026Article
- Perioperative outcomes of total and unicompartmental knee arthroplasty in patients with Type 2 diabetes mellitus: A propensity score-matched analysis.Journal of experimental orthopaedics · 2026Article
- Article
- Functional Outcomes of Total Hip Arthroplasty using Modified Harris Hip Score and Oxford Hip Score: A Prospective Study.Journal of orthopaedic case reports · 2026Article
- Cemented total hip arthroplasty reduces early complications: a Japanese nationwide propensity-matched study.Archives of orthopaedic and trauma surgery · 2026Article
- Long-Term Results of Medial Fixed-Bearing Unicompartmental Knee Arthroplasty with Miller-Galante Prosthesis: A Minimum 10-Year Follow-Up Study.Medicina (Kaunas, Lithuania) · 2026Article
- Tranexamic acid reduces transfusion requirements after pelvic osteotomy: a nationwide propensity score-matched analysis.Archives of orthopaedic and trauma surgery · 2026Article
- Association between medial femoral resection thickness and postoperative pain after fixed-bearing unicompartmental knee arthroplasty: an exploratory cohort study.BMC musculoskeletal disorders · 2026Article
- Smoking increases the risk of early postoperative infection after elective total hip arthroplasty: Evidence from a Nationwide Japanese database.International orthopaedics · 2026Article
- Association of preoperative serum 25-hydroxyvitamin D levels with deep vein thrombosis after total knee arthroplasty: a hypothesis-generating analysis of coagulation function mechanisms.Frontiers in surgery · 2026Article
- Impact of navigation assistance on perioperative outcomes in UKA: A nationwide propensity score-matched cohort study.Journal of experimental orthopaedics · 2026Article
- Evaluating In-Hospital Safety and Perioperative Costs of Total Hip Arthroplasty in Super-Elderly Patients: A Nationwide Propensity Score-Matched Analysis in Japan.Journal of clinical medicine · 2025Article
- Mobile Versus Fixed-Bearing in Medial Unicompartmental Knee Arthroplasty: An Average 10-Year Follow-Up.Journal of clinical medicine · 2025Article
- Delayed-Onset Pseudoaneurysm of the Superior Lateral Genicular Artery Following Total Knee Arthroplasty: A Case Report.Clinical medicine insights. Case reports · 2025Article
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9 authors.
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Abstract
introductionTotal knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) are widely used to treat knee osteoarthritis. TKA significantly contributes to long-term pain relief and joint function improvement, while UKA offers faster recovery and reduced early complications. However, TKA and UKA complication risks, aside from conditions such as deep vein thrombosis, have not been thoroughly investigated. This study compares the in-hospital complication risks of TKA and UKA using a nationwide Japanese database.
methodsA retrospective cohort study was conducted using data from the Japanese Diagnosis Procedure Combination (DPC) database, spanning from April 2016 to March 2023. A total of 259,319 knee arthroplasty cases (TKA: 228,595; UKA: 30,724) were analyzed. Propensity score matching (1:1) was used to adjust for age, sex, comorbidities, and surgical factors, resulting in 30,591 matched pairs. Multivariable logistic regression analyses assessed the risks of complications, including deep vein thrombosis, pulmonary embolism, and surgical site infections.
resultsDeep vein thrombosis is frequently observed as a complication with a high incidence rate. Even after propensity score matching, the incidence remained significantly higher in the TKA group (8.8%) compared with the UKA group (6.1%) (p < 0.0001). TKA was associated with significantly higher risks of deep vein thrombosis (odds ratio (OR): 1.467, 95% confidence interval (CI) 1.380-1.560, p < 0.0001), pulmonary embolism (OR: 1.709, 95% CI 1.182-2.470, p = 0.0044), and surgical site infection (OR: 1.512, 95% CI 1.277-1.790, p < 0.0001) compared with UKA. UKA showed lower risks of cognitive dysfunction, pneumonia, transfusion requirements, and shorter hospital stays. However, patients who underwent UKA had a higher risk of periprosthetic fractures.
conclusionsThis study highlights the distinct risk profiles of TKA and UKA, emphasizing the need for tailored surgical decision-making. UKA offers advantages in reducing complications for specific patient populations. Strengthening prophylactic measures is crucial for effectively managing thromboembolic and infectious complications in patients undergoing TKA.
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