Evidence map›Paper›PMID 40341059›Full record

ArticleJournal of the National Comprehensive Cancer Network : JNCCN2025

Trends in Prevalence and Correlates of Alcohol Use Disorder Diagnoses Among US Adult Cancer Survivors: Serial Cross-Sectional Analysis.

Anton L V Avanceña, Jyun-Heng Lai, Mary M Velasquez, Corwin M Zigler, Christopher R Frei, Michael Pignone

Abstract read
In one paragraph

Article in Journal of the National Comprehensive Cancer Network : JNCCN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anton L V AvanceñaHealth Outcomes Division, College of Pharmacy, The University of Texas at Austin, Austin, TX.
Jyun-Heng LaiHealth Outcomes Division, College of Pharmacy, The University of Texas at Austin, Austin, TX.
Mary M VelasquezHealth Behavior Research and Training Institute, Steve Hicks School of Social Work, The University of Texas at Austin, Austin, TX.
Corwin M ZiglerDepartment of Statistics and Data Sciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX.
Christopher R FreiPharmacotherapy and Translational Sciences Division, College of Pharmacy, The University of Texas at Austin, Austin, TX.
Michael PignoneDepartment of Medicine, Duke University School of Medicine, Durham, NC.

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUM1TR004538 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ROBERT A CLARK, Kenneth M Hargreaves · 2023 to 2026
$22.3M
CTSA K12 Program at The University of Texas Health Science Center at San AntonioK12TR004529 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ALISON G CAHILL, JOEL TSEVAT · 2023 to 2026
$4.1M
NCATS NIH HHS K12 TR004529NCATS NIH HHS UM1 TR004538
6 · The paper itself

Abstract

backgroundAlcohol use disorder (AUD) is associated with cancer recurrence, new malignancies, and mortality among survivors of certain cancers. This study evaluated trends (2012-2021) in prevalence and correlates of AUD diagnoses among adult cancer survivors in the United States.

methodsThis retrospective, serial cross-sectional study used claims data (2011-2021) from a national sample of US individuals with employer-sponsored health insurance. Adults diagnosed with malignant neoplasms who had at least 6 months of continuous health insurance enrollment prior to their cancer diagnosis were included. The primary outcome was a recent AUD diagnosis in each year of the study period identified from inpatient and outpatient records. We assessed AUD prevalence for each year among all cancer survivors and in specific subgroups. Using data from 2021, we compared sociodemographic and clinical characteristics between cancer survivors with and without AUD diagnoses and identified correlates of AUD diagnosis by using multivariable logistic regression.

resultsOf 5,956,137 eligible cancer survivors, 105,778 (1.78%) had received an AUD diagnosis. The annual prevalence of AUD diagnoses increased from 0.78% in 2012 to 1.43% in 2021 (P<.0001). AUD prevalence also increased in specific subgroups, including individuals with alcohol-related cancers (from 0.88% to 1.61%; P<.0001) and those receiving antineoplastic agents (from 0.97% to 1.60%; P<.0001). Multivariable logistic regression analysis demonstrated that male sex, alcohol-related cancers, mental health diagnoses, and other substance use disorders were associated with at least 2 to 5 times greater odds of an AUD diagnosis.

conclusionsAUD diagnosis among US cancer survivors with private health insurance has increased over time, mirroring trends in the general population. Integrating AUD screening and treatment into cancer care may help mitigate the unique risks associated with alcohol use and misuse in cancer survivors.

Indexed as

AlcoholismCancer SurvivorsNeoplasmsAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesUnited StatesYoung Adult

Identifiers

PMID40341059
PMCPMC12211465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.