ArticleBMJ paediatrics open2025
Association between cerebral oxygen saturation and neurological injury in asphyxiated neonates in a middle-income country: a retrospective cohort study.
Article in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundNeonatal outcomes following perinatal asphyxia vary significantly between low- and middle-income countries (LMICs) and high-income settings. Near-infrared spectroscopy is a non-invasive method for monitoring regional cerebral oxygen saturation (rScO
methodsA retrospective longitudinal study was conducted on term neonates with moderate-to-severe perinatal asphyxia undergoing TH at a high-complexity healthcare institution in an LMIC. Continuous rScO
results88 neonates were included, of which 29 had abnormal MRI findings. All patients were referred from lower-complexity centres. Elevated rScO
conclusionsHigher rScO₂ values during the first 6 hours of TH were associated with abnormal brain MRI findings. Although not definitive, early rScO
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