Evidence map›Paper›PMID 40340567›Full record

SynthesisFuture cardiology2025

Nicorandil for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a meta-analysis.

Ayesha Shaukat, Muhammad Ahmed Zahoor, Laiba Shakeel, Muniba Ijaz, Zobia Ahmad, Wajiha Zehra, Zaigham Ali, Muhammad Umar Mian, Rabbia Munsab, Zainab Awan and 7 more

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Future cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ayesha ShaukatDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muhammad Ahmed ZahoorDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Laiba ShakeelDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muniba IjazDepartment of Medicine, Allama Iqbal Medical College, Lahore, Pakistan.
Zobia AhmadDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Wajiha ZehraDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Zaigham AliDepartment of Medicine, Karachi Medical and Dental College, Karachi, Pakistan.
Muhammad Umar MianDepartment of Medicine, Allama Iqbal Medical College, Lahore, Pakistan.
Rabbia MunsabDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Zainab AwanDepartment of Medicine, Liaquat National Hospital and Medical College, Karachi, Pakistan.
Ismat FatimaDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Simran Suleman PanjwaniDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muhammad TahaDepartment of Medicine, Karachi Medical and Dental College, Karachi, Pakistan.
Juvairia YousufDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muhammad HasanainDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muhammad Umair AnjumDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Muhammad Omar LarikDepartment of Medicine, Dow International Medical College, Karachi, Pakistan.ORCID 0000-0002-2328-6801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionContrast-induced nephropathy (CIN) is a feared complication of angiographic procedures, resulting in a sudden decline in renal function.

methodsPubMed, ScienceDirect, and Google Scholar were searched for potentially relevant articles from inception till August 2024. The meta-analysis was conducted using RevMan 5.4 with risk ratios (RR), mean differences (MD), and 95% confidence intervals (95% CI) computed.

resultsUltimately, 13 studies were incorporated in the analysis. Nicorandil portrayed a significant protective effect against CIN (RR: 0.42; 95% CI: 0.33-0.54;

conclusionNicorandil has promising efficacy and safety in reducing the risk of CIN. However, further trials are necessary in order to validate our conclusions.

Indexed as

Acute Kidney InjuryContrast MediaCoronary AngiographyKidney DiseasesNicorandilHumansVasodilator AgentsContrast MediaNicorandilVasodilator Agentscontrast-induced nephropathycoronary angiographymeta-analysisNicorandilpercutaneous coronary intervention

Identifiers

PMID40340567
PMCPMC12506717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.