Evidence map›Paper›PMID 40340531›Full record

ArticleCell transplantation

Selective TCRαβ+ and CD45RA+ T-cell depletion of hematopoietic stem cell graft: An analysis on factors that affect depletion performance.

Chieh Hwee Ang, Gina Gan, Ren How Ho, Kee Khiang Heng, Yeh Ching Linn

Abstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chieh Hwee AngDepartment of Hematology, Singapore General Hospital, Singapore.ORCID 0000-0003-0572-7455
Gina GanDepartment of Hematology, Singapore General Hospital, Singapore.
Ren How HoDepartment of Hematology, Singapore General Hospital, Singapore.
Kee Khiang HengDepartment of Hematology, Singapore General Hospital, Singapore.
Yeh Ching LinnDepartment of Hematology, Singapore General Hospital, Singapore.ORCID 0000-0001-8098-2590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective depletion of TCRαβ+ and CD45RA+ subsets of apheresed hematopoietic progenitor cells, HPC(A), enables haploidentical hematopoietic stem cell transplant (haplo-HSCT) by circumventing risks of graft-versus-host disease. Here, we analyze our institution's large series of

Indexed as

Hematopoietic Stem CellsHematopoietic Stem Cell TransplantationLeukocyte Common AntigensLymphocyte DepletionReceptors, Antigen, T-Cell, alpha-betaT-LymphocytesAdolescentAdultAntigens, CD34FemaleHematopoietic Stem Cell MobilizationHumansMaleMiddle AgedYoung AdultAntigens, CD34Leukocyte Common AntigensReceptors, Antigen, T-Cell, alpha-betaCD45RA depleted memory T cellgraft compositionhaploidentical hematopoietic stem cell transplantselective T-cell depletionTCRαβ depleted stem cell

Identifiers

PMID40340531
PMCPMC12062598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.