ArticleApplied and environmental microbiology2025
Molecular adaptations specific to extreme halophilic archaea could promote high perchlorate tolerance.
Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Diversity of Archaea.Progress in molecular and subcellular biology · 2026Review
- Enhancing UV-C and perchlorate resistance inFrontiers in microbiology · 2026Article
- Halotolerant bacteria from mangrove and restinga ecosystems in Camocim, Brazil: astrobiological relevance and biotechnological potential.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Planetary microbiology: microbes, planets, and the search for life.Applied and environmental microbiology · 2025Article
- Halophiles and Halotolerants: From Industry to Astrobiology.Current microbiology · 2025Review
Corrections and comments
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Authors and funding
2 authors.
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Abstract
Perchlorate is a strong chaotropic agent that causes macromolecule denaturation, DNA damage, and oxidative stress. However, perchlorate deliquescence is thought to promote the formation of liquid salt brines, even at hyper-arid and cold environments, such as the Martian regolith. For that reason, the detection of high levels of perchlorate at different locations on the Martian surface led to hypotheses about the existence of Martian microenvironments compatible with life, especially with those organisms tolerant to hyper-salinity and perchlorate. Extreme halophilic archaea have been proposed as the best candidates to inhabit those environments not only due to their high tolerance to salinity and perchlorate, but also because of their resistance to a wide variety of stress conditions. Since specific perchlorate responses remain largely unknown, in this work, we have analyzed the molecular mechanisms of perchlorate tolerance exhibited by the model extreme halophilic archaeon
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