Evidence map›Paper›PMID 40340330›Full record

ArticleACS nano2025

High-Resolution Correlative Microscopy Approach for Nanobio Interface Studies of Nanoparticle-Induced Lung Epithelial Cell Damage.

Rok Podlipec, Luka Pirker, Ana Krišelj, Gregor Hlawacek, Alessandra Gianoncelli, Primož Pelicon

Abstract read
In one paragraph

Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Two-Photon 3D Printing of Functional Microstructures Inside Living Cells.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rok PodlipecJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.ORCID 0000-0001-8584-3274
Luka PirkerJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Ana KrišeljJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Gregor HlawacekInstitute for Ion Beam Physics and Materials Research, Helmholtz-Zentrum Dresden-Rossendorf e.V., Bautzner Landstrasse 400, 01328 Dresden, Germany.ORCID 0000-0001-7192-716X
Alessandra GianoncelliElettra, Sincrotrone Trieste, Strada Statale 14 km 163.5 in AREA Science Park, Trieste 34149, Italy.ORCID 0000-0002-2457-3618
Primož PeliconJožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.ORCID 0000-0003-2469-3342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Correlated light and electron microscopy (CLEM) has become essential in life sciences due to advancements in imaging resolution, sensitivity, and sample preservation. In nanotoxicology─specifically, studying the health effects of particulate matter exposure─CLEM can enable molecular-level structural as well as functional analysis of nanoparticle interactions with lung tissue, which is key for the understanding of modes of action. In our study, we implement an integrated high-resolution fluorescence lifetime imaging microscopy (FLIM) and hyperspectral fluorescence imaging (fHSI), scanning electron microscopy (SEM), ultrahigh resolution helium ion microscopy (HIM) and synchrotron micro X-ray fluorescence (SR μXRF), to characterize the nanobio interface and to better elucidate the modes of action of lung epithelial cells response to known inflammatory titanium dioxide nanotubes (TiO

Indexed as

Epithelial CellsLungNanoparticlesTitaniumHumansMicroscopy, FluorescenceNanotubesParticle SizeTitaniumtitanium dioxidecorrelated light and electron microscopyhelium ion microscopylung epithelium inflammationnanobio interfacesynchrotron micro X-ray fluorescenceTiO2 nanotubes

Identifiers

PMID40340330
PMCPMC12096433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.