Evidence map›Paper›PMID 40339051›Full record

ArticlePLOS global public health2025

Does enhanced HIV prevention, diagnosis, and linkage to care reduce hospitalisation in high HIV-burden communities in Zambia and South Africa? findings from the HPTN 071 (PopART) randomised trial.

Ronelle Burger, Nomtha Bell-Mandla, Abigail Harper, Sean Richardson, Sarah Kanema, Ranjeeta Thomas, Lawrence Mwenge, Ethan Wilson, Sian Floyd, Peter Bock and 5 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01900977 (Population Effects of Antiretroviral Therapy to Reduce HIV Transmission), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01900977 nacompletednot on this map

Population Effects of Antiretroviral Therapy to Reduce HIV Transmission (PopART): A Cluster-randomized Trial of the Impact of a Combination Prevention Package on Population-level HIV Incidence in Zambia and South Africa

TypeinterventionalSponsorHIV Prevention Trials NetworkRan2014 to 2018Enrolled48,540ConditionsHIVArmsUniversal Testing with immediate ART, Universal Testing with ART eligibility according to National Guidelines, Standard of Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ronelle BurgerEconomics Department, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0003-2463-5265
Nomtha Bell-MandlaDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
Abigail HarperDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
Sean RichardsonErasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0009-0000-9370-9112
Sarah KanemaUniversity of Zambia, Lusaka, Zambia.
Ranjeeta ThomasDepartment of Health Policy, London School of Economics and Political Science, London, United Kingdom.ORCID https://orcid.org/0000-0002-0947-4574
Lawrence MwengeUniversity Teaching Hospitals, Lusaka, Zambia.
Ethan WilsonFred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Sian FloydDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Peter BockDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-3211-6078
Helen AylesDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Sarah FidlerDepartment of Medicine, Faculty of Medicine, Imperial College, London, United Kingdom.
Richard HayesDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-1729-9892
Katharina HauckMRC Centre for Global Infectious Disease Analysis & Jameel Institute for Disease and Emergency Analytics, School of Public Health, Imperial College London, London, United Kingdom.
HPTN 071 (PopART) study team

Funding

Stellenbosch University Clinical Trial Unit, Cape Town, South AfricaUM1AI069521 · NIAID · STELLENBOSCH UNIVERSITY · PI Shaun Barnabas, Anneke Catharina Hesseling · 2012 to 2026
$21.5M
NIAID NIH HHS UM1 AI069521
6 · The paper itself

Abstract

trial registrationClinicalTrials.gov NCT01900977.

Identifiers

PMID40339051
PMCPMC12061103

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.