SynthesisPLoS neglected tropical diseases2025
The psychosocial and emotional burden of lymphatic filariasis: A systematic review.
Synthesis in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions to improve the psychosocial outcomes of individuals with lymphedema: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Surgical Intervention for Filariasis-Induced Lymphedema: A Systematic Review of Ablative and Physiological Approaches.Life (Basel, Switzerland) · 2026Review
- Tailored personas for self-management in home-based rehabilitation for participants with lower limb lymphedema: A qualitative study.International journal of nursing studies advances · 2026Article
- Tetracycline Resistance Pattern Among Lymphatic Filariasis-Hyperendemic Communities in Southern Ghana: A Mixed-Method Approach.Health science reports · 2026Article
- Advanced machine learning approaches for predicting Neglected Tropical Disease co-endemicity in Kenya: A focus on soil-transmitted helminths, schistosomiasis, and lymphatic filariasis.PLoS neglected tropical diseases · 2026Article
- mRNA based vaccines and therapeutics for parasitic infections: a comprehensive review.Journal of nanobiotechnology · 2025Review
- Living with Filariasis: Unseen Struggles of a Neglected Disease.The Yale journal of biology and medicine · 2025Review
- Two decades of filariasis in India: Insights into prevalence, diagnostic challenges, and strategies for elimination by 2027.IJID regions · 2025Review
- An Unusual Presentation of Human Parotid Filariasis.Tropical medicine and infectious disease · 2025Article
- Correlation Between Alexithymia, Illness-Related Stigma, and Self-Esteem in Patients With Lymphedema: A Cross-Sectional Study.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLymphatic filariasis (LF) is a neglected tropical disease affecting an estimated 882.5 million people at risk of infection. It is caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori, leading to lymphedema, and severe deformation of extremities and resulting in both physical and mental health consequences. Affected individuals often suffer from depression, anxiety, and anger, exacerbated by disability, marginalization, and societal rejection due to their physical disability.
methodsA systematic review of the literature was conducted following the PRISMA guidelines, using the PubMed, Scopus, and Scielo databases without date restrictions, and including articles in both Spanish and English. The quality of selected articles was evaluated using the Newcastle-Ottawa Quality Assessment Scale and the JBI critical appraisal checklist. Our protocol was registered in PROSPERO under de code: CRD42024537760.
resultsA total of 23 studies were included in this analysis, which identified the emotional impact of LF. Common symptoms include depression, anxiety, frustration, anger, and feelings of inferiority. Physical disability caused by lymphedema led to societal rejection, contributing to the development of these symptoms. We also found that the severity or advancement of the disease correlated with an increased emotional and social impact.
conclusionsLF significantly impacts the quality of life due to both its physical and emotional consequences. Psychological support for affected individuals is crucial from diagnosis, and the education of transmission and treatment of LF in endemic communities is essential to prevent discrimination and exclusion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.