Evidence map›Paper›PMID 40338645›Full record

ArticleSocial cognitive and affective neuroscience2025

Effects of oxytocin on agency in anxiously attached individuals: a replication and extension.

Jennifer A Bartz, Willis Klein, Amy J P Gregory

Abstract read
In one paragraph

Article in Social cognitive and affective neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer A BartzDepartment of Psychology, McGill University, Montréal, Québec, H3A 1G1, Canada.ORCID 0000-0001-5043-9458
Willis KleinDepartment of Psychology, McGill University, Montréal, Québec, H3A 1G1, Canada.
Amy J P GregoryDepartment of Psychology, McGill University, Montréal, Québec, H3A 1G1, Canada.

Funding

Development GrantNatural Sciences and Engineering Research Council
6 · The paper itself

Abstract

Oxytocin can promote prosocial behaviour but also result in anti-social effects in anxiously attached individuals. Such individuals desire interpersonal closeness but are preoccupied with abandonment; they also lack agency (self-efficacy, empowerment), possibly because of thwarted attachment needs. By augmenting affiliative strivings, oxytocin may threaten anxiously attached individuals' already fragile sense of agency. Indeed, prior work shows that oxytocin increases communion, especially for avoidant individuals, but decreases agency for anxious individuals. Here, we replicated the oxytocin-avoidance-communion effect (P < .001), with some additional nuance, and the oxytocin--anxiety-agency effect (P = .014) in a larger (N = 77; within-subject), gender diverse sample. We also investigated bodily agency using the rubber hand illusion paradigm. Anxious individuals also evidenced less bodily agency-experiencing greater 'loss of own hand'-although this was not potentiated by oxytocin. These findings may explain some of oxytocin's divergent social effects and highlight the tension that can arise between meeting needs for communion/security and agency in interpersonally vulnerable individuals.

Indexed as

AnxietyObject AttachmentOxytocinAdolescentAdultFemaleHumansIllusionsMaleYoung AdultOxytocinagencyattachmentcommunionoxytocinrubber hand illusion

Identifiers

PMID40338645
PMCPMC13223751

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.