Evidence map›Paper›PMID 40338510›Full record

ArticleJournal of autism and developmental disorders2025

Cognitive Behavioral Therapy for Autistic School-Aged Children with Interfering Anxiety: Impact on Caregiver-Defined Goals.

Jeffrey J Wood, Kashia A Rosenau, Virginia Muscatello, Kate Cooper, Karen S Wood, Philip C Kendall, Eric A Storch

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02028247 (2/3 Treatment of Anxiety in Autism Spectrum Disorder), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02028247 nacompletednot on this map

2/3 Treatment of Anxiety in Autism Spectrum Disorder

TypeinterventionalSponsorUniversity of South FloridaRan2014 to 2018Enrolled214ConditionsAutism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise SpecifiedArmsPersonalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey J WoodDepartment of Education, University of California, Los Angeles, USA. jeffwood@ucla.edu.ORCID http://orcid.org/0000-0002-0759-6156
Kashia A RosenauDavid Geffen School of Medicine, University of California, Los Angeles, USA.
Virginia MuscatelloDepartment of Education, University of California, Los Angeles, USA.
Kate CooperDepartment of Clinical, Educational and Health Psychology, University College London, London, UK.
Karen S WoodDavid Geffen School of Medicine, University of California, Los Angeles, USA.
Philip C KendallDepartment of Psychology and Neuroscience, Temple University, Philadelphia, PA, USA.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.

Funding

1/3 Treatment of Anxiety in Autism Spectrum DisorderR01HD080098 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOOD, JEFFREY JAMES · 2014 to 2016
$663k
National Institute of Child Health and Human Development R01HD080096National Institute of Child Health and Human Development R01HD080097National Institute of Child Health and Human Development R01HD080098NICHD NIH HHS R01 HD080098
6 · The paper itself

Abstract

purposeAutistic children and youth can experience both mental health and adaptive skill needs, making the assessment of high priority goals from the caregiver's standpoint an important objective in psychological treatment planning. Modular cognitive behavioral therapy (CBT) tailored to each family's goals may be optimally suited to addressing different treatment priorities in autistic youth with interfering anxiety. The present study investigated the effects of adapted, modular CBT as compared to standard-of-practice CBT and treatment-as-usual (TAU) on caregiver-defined treatment goals.

methodsA multisite randomized, controlled trial compared an adapted, modular CBT program with standard-of-practice CBT and TAU for autistic youth with interfering anxiety (N = 167; aged 7-13 years). At baseline, caregivers described their child's three highest priority clinical needs in their own words and rated the severity of these problems on a Likert-type scale, using the Youth Top Problems (YTP) scale. A broad range of clinical needs (e.g., internalizing, externalizing, and autism-related needs) were described by caregivers on this measure. At each treatment session, these problems were rated by caregivers. Youth coping was rated by caregivers each month.

resultsYouth randomized to adapted CBT exhibited more rapid reductions in total YTP ratings in comparison with the TAU and standard-of-practice CBT conditions over the course of 16 weeks. Increased youth coping partly mediated this effect.

conclusionIn adapted/modular CBT, the treatment emphasis can be readily adjusted to address caregiver-defined goals and this feature may contribute to its advantage in reducing scores on a personalized measure of treatment goals. TRIAL REGISTRATION NUMBER(S): ClinicalTrials.gov NCT02028247.

Indexed as

AnxietyAutismCaregiver-defined outcomesCognitive-behavioral therapyCoping

Identifiers

PMID40338510

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.