Evidence map›Paper›PMID 40338444›Full record

ArticleAMB Express2025

In vitro investigation of Mangifera indica L. peel extracts: antibacterial, antioxidant, and docking studies.

Salwa M El-Sayed, Basma T Abd-Elhalim, Khalid A El-Dougdoug, Rawia F Gamal, Ghada G El-Bana, Nesma Nabil Ibrahim Mohamed

Abstract read
In one paragraph

Article in AMB Express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Adaptive Responses of Tropical Crops: A Multi-Scale Omics Integrated Perspective.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Salwa M El-SayedDepartment of Biochemistry, Faculty of Agriculture, Ain Shams University, PO Box 68, Hadayek Shoubra,Cairo, 11241, Egypt.
Basma T Abd-ElhalimDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, Cairo, 11241, Egypt. basma.talaat@agr.asu.edu.eg.
Khalid A El-DougdougDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, Cairo, 11241, Egypt.
Rawia F GamalDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, Cairo, 11241, Egypt.
Ghada G El-BanaDepartment of Chemistry, Faculty of Science, Mansoura University, El-Gomhoria Street, Mansoura, 35516, Egypt.
Nesma Nabil Ibrahim MohamedDepartment of Biochemistry, Faculty of Agriculture, Ain Shams University, PO Box 68, Hadayek Shoubra,Cairo, 11241, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marketers of antioxidants and antimicrobials view fruit peels as a special, readily available, reasonably priced, natural, eco-friendly, and lucrative source. Mangos (Mangifera indica L.) and their byproduct peels and kernels are nutrient-dense, distinctive, affordable, efficient, natural, and environmentally friendly sources of antibacterial agents, antioxidants, and other active chemicals. The current study aimed to prepare extracts of different degrees of polarity from mango peels, detect their active phytochemical compounds, and study their effects as antioxidants, antibacterials against food-borne pathogens, anti-biofilms, and anti-colon cancer in vitro. Phytochemical classes of compounds were screened using different standard methods. The most promising profile was for mango peel ethyl acetate extract (MPEE) due to the presence of a variety of phytochemicals including tannin, coumarin, alkaloids, flavonoids, phenols, steroids, and terpenoids at high concentrations compared to other mango peel extracts. Therefore, it was selected as the most valuable extract to examine its anti-colon cancer impact, anti-foodborne pathogenic bacteria, and antibiofilm. The anti-foodborne pathogenic activity of MPEE was evaluated against Enterococcus faecalis ATCC 7080, Staphylococcus aureus ATCC 5638, Salmonella typhi DSM17058, Bacillus cereus ATCC 11778, Shigella sonnei DSM 5570, and Escherichia coli ATCC 8739 that showed highly impact for all. At MIC and MBC values of 500 μg/ml, the MPEE had a 100% bactericidal spectrum; at lower concentrations of 125-250 µg/ml, no antibacterial action was seen. The MPEE had a biofilm inhibition percentage ranging between 98.75-53.33%; B. cereus had the highest percentage and S. sonnei had the lowest. Furthermore, The MPEE demonstrated an anticancer activity against human colon epithelium ATB-37 (Caco2) with an IC

Indexed as

AntibacterialAntibiofilmAntioxidant activityColon cancerMango peelsPhytochemical screening

Identifiers

PMID40338444
PMCPMC12061830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.