Evidence map›Paper›PMID 40338392›Full record

ArticleHead and neck pathology2025

Primordial Odontogenic Tumor in Anterior Mandible: A Case Image.

José Martins Figueredo Junior, Jaqueline Vaz Vanini, Giovanna Lopes Carvalho, Ramon Ribeiro, Daniele Heguedusch, Décio Dos Santos Pinto Junior, Elio Hitoshi Shinohara, Fabio Daumas Nunes

Abstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José Martins Figueredo JuniorDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil. jose.figueredo@usp.br.
Jaqueline Vaz VaniniDepartment of Cariology, Restorative Sciences & Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Giovanna Lopes CarvalhoDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil.
Ramon RibeiroDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil.
Daniele HegueduschDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil.
Décio Dos Santos Pinto JuniorDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil.
Elio Hitoshi Shinohara, São Paulo, SP, Brazil.
Fabio Daumas NunesDepartment of Pathology, School of Dentistry, Universidade de São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP, 05508-000, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304389/2015-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.932709/2024-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.965101/2024-00Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/04287-4
6 · The paper itself

Abstract

The primordial odontogenic tumor (POT) is a rare mixed odontogenic tumor believed to develop during early odontogenesis. It is composed of a fibromyxoid stroma with proliferation of mesenchymal cells surrounded by a layer of columnar cells exhibiting reverse polarity and pale cytoplasm. This article presents a case of primordial odontogenic tumor in the anterior region of the mandible of a 10-year-old male Caucasian patient who presented with an expansive intraosseous lesion in the anterior portion of the mandible and a delay in tooth eruption, with a 1-year history of asymptomatic swelling. An incisional biopsy was performed and sent to an external pathology service that diagnosed as ameloblastoma. The clinician sent the paraffin block and hematoxylin/eosin (H&E) slides for diagnosis review to the University of São Paulo, Oral Pathology Service. The H&E slides revealed an abundant myxoid cell-rich stroma containing a few islands of ameloblastic-like epithelium and areas of loosely arranged stellate/spindle-shaped cells resembling stellate reticulum. The odontogenic-like epithelium was also noted at the periphery of the specimen, as well as discrete areas of hyalinization. Cellular pleomorphism and mitotic figures were not observed, supporting the diagnosis of ameloblastic fibroma. The clinician proceeded with surgical excision and sent us the whole specimen. After reviewing the slides and discussing the case, the final diagnosis was primordial odontogenic tumor. This report is relevant to provide more information for clinicians and pathologists about this rare entity.

Indexed as

AmeloblastomaMandibular NeoplasmsOdontogenic TumorsChildHumansMaleOdontogenic tumorOral pathologySoft tissue neoplasm

Identifiers

PMID40338392
PMCPMC12061800

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