Evidence map›Paper›PMID 40338380›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Moving from theory to practice: implementing a prehabilitation program before gastrointestinal cancer surgery (PREHAB-GI).

Kristy-Lee Raso, Michael Suen, Sam Egger, Jane Turner, Sonia Khatri, Yanlan Lin, Carolyn Wildbore, Caoimhe Scales, Shannon Gerber, Kin Yin Carol Chan and 4 more

Abstract read
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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prehabilitation for cancer surgery: a systematic review of qualitative literature from experienced stakeholders.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Pooled it
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kristy-Lee RasoDepartment of Nutrition and Dietetics, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Michael SuenSydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Sam EggerThe Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council NSW, Sydney, New South Wales, Australia.
Jane TurnerConcord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Sonia KhatriDepartment of Colorectal Surgery, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Yanlan LinDepartment of Colorectal Surgery, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Carolyn WildboreConcord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Caoimhe ScalesConcord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Shannon GerberConcord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Kin Yin Carol ChanConcord Cancer Centre, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Guillermo Becerril-MartinezSydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Philip Le PageDepartment of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Sim Yee Cindy TanDepartment of Nutrition and Dietetics, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Janette VardySydney Medical School, University of Sydney, Sydney, New South Wales, Australia. janette.vardy@sydney.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgery remains the primary treatment for early-stage colorectal and upper gastrointestinal (UGI) cancers. However, it can lead to postoperative complications and reduced functionality. Prehabilitation aims to improve functional reserves before surgery. We aimed to evaluate the implementation of a multimodal prehabilitation program in "real-world" patients undergoing gastrointestinal cancer surgery.

methodsAn implementation study evaluating prehabilitation in patients undergoing gastrointestinal (colorectal or UGI) cancer surgery at Concord Hospital. The prehabilitation program included supervised exercise, nutrition and nursing support delivered face-to-face or by telehealth (COVID-19 adaptations). ASSESSMENTS: baseline, pre-surgery and 30 days after surgery. PRIMARY OUTCOME: implementation using the RE-AIM (Reach/Effectiveness/Adoption/Implementation/Maintenance) framework. SECONDARY OUTCOMES: functional, nutritional and surgical outcomes, with comparisons to historical controls.

resultsBetween January 2020 and December 2021, 181 patients were screened; 91 (50%) were eligible. Reach: 77/91 recruited (63 colorectal, 14 UGI). Median age, 70 years (IQR, 59-79); 60% were males. Median intervention duration, 16 days (IQR, 12.25-19.75). EFFECTIVENESS: quality of life, anxiety and functional capacity improved from baseline to pre-surgery (6-min walk test (+16.1 m, p=0.038) and 2-min step test (+10.0 steps, p<0.001)). Compared to historical controls, hospital length of stay was reduced by 2.1 days (p=0.010), with no differences in complications. Adoption: 91% of referrals came directly from surgeons. IMPLEMENTATION: 94% completed the intervention, with high adherence and satisfaction levels. Maintenance: after study completion, the program was incorporated into standard care with some modifications.

conclusionsPrehabilitation can be implemented in a real-world setting, with a trend towards improving functional and surgical outcomes, but dedicated resources are necessary to implement and maintain the program.

Indexed as

Colorectal NeoplasmsGastrointestinal NeoplasmsPreoperative CarePreoperative ExerciseAgedCOVID-19FemaleHumansMaleMiddle AgedPostoperative ComplicationsTelemedicineExerciseGastrointestinal cancerImplementationNutritionPrehabilitationSurgery

Identifiers

PMID40338380
PMCPMC12062105

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.