SynthesisWorld journal of urology2025
Analgesic effects of erector spinae plane block in patients undergoing nephrectomy: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative pain management remains a massive challenge after renal surgeries. The erector spinae plane block (ESPB) is a promising regional analgesia for pain management after nephrectomy. Unlike other regional anesthesia techniques, ESPB is relatively simple to perform and has been shown to provide effective pain relief in various surgical contexts. We aim to evaluate the analgesic effects of ESPB after nephrectomy, with the goal of providing evidence-based guidance for postoperative pain management in nephrectomy patients.
methodsA comprehensive and meticulous literature search was conducted on PubMed, Scopus, Web of Science, and Cochrane Library till September 2024. Review Manager software was used to pool dichotomous and continuous data. We employed the risk of bias tool to evaluate the quality of the evidence, ensuring a thorough and robust analysis.
resultsThis systematic review identified fourteen clinical trials of 897 patients that met the inclusion criteria. Meta-analysis results demonstrated that the ESPB significantly reduced pain scores at rest compared to no block at 30 min, 1 h, and 2 h postoperatively (p < 0.00001). In the intermediate recovery phase, ESPB also resulted in significantly lower pain scores at 4, 6, and 12 h (p < 0.001). At 24 h, ESPB continued to show a significant pain reduction compared to no block (SMD = -0.65, p < 0.0001). Less opioid consumption and prolonged time to first rescue analgesia were noticed in ESPB groups (MD = -29.56 mg, p < 0.00001), (SMD = 3.56 min, p = 0.001) respectively. ESPB showed a lower risk of postoperative nausea and vomiting.
conclusionThis review demonstrated significant postoperative analgesic effects of ESPB with lower risks of postoperative nausea and vomiting in nephrectomy. However, the need for further studies to provide conclusive evidence is urgent and paramount in our field.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.