Evidence map›Paper›PMID 40338298›Full record

ReviewDermatologie (Heidelberg, Germany)2025

[Value of surgery for malignant melanoma in the context of current adjuvant and neoadjuvant treatment concepts].

Mareike Alter, Ralf Gutzmer

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mareike AlterKlinik für Dermatologie, Venerologie, Allergologie und Phlebologie, Johannes Wesling Klinikum, Mühlenkreiskliniken AöR, Universitätsklinikum der Ruhr Universität Bochum, Hans-Nolte-Str. 1, 32429, Minden, Deutschland. Mareike.Alter@muehlenkreiskliniken.de.
Ralf GutzmerKlinik für Dermatologie, Venerologie, Allergologie und Phlebologie, Johannes Wesling Klinikum, Mühlenkreiskliniken AöR, Universitätsklinikum der Ruhr Universität Bochum, Hans-Nolte-Str. 1, 32429, Minden, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of melanoma treatment is also dynamic with respect to surgical procedures. In the treatment of the primary tumor the safety margins have been reduced based on study data. In surgery of the regional lymph nodes elective lymph node dissection has been discontinued in favor of sentinel lymph node (SLN) extirpation. Whether SLN extirpation can even be dispensed with in view of adjuvant treatment, particularly in patients with thicker primary tumors, needs to be further investigated. In the stage of regional macrometastasis, neoadjuvant or perioperative drug treatment should be considered before surgical measures. In the case of distant metastasis and disseminated disease, systemic treatment is also the first choice and in the case of local complications or oligoprogression under systemic treatment, surgical measures can also be considered.

Indexed as

MelanomaNeoadjuvant TherapySkin NeoplasmsChemotherapy, AdjuvantHumansLymphatic MetastasisLymph Node ExcisionMargins of ExcisionSentinel Lymph Node BiopsyOligoprogressionPerioperative drug treatmentSafety marginsSentinel lymph nodesTumor thickness

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.