Evidence map›Paper›PMID 40338114›Full record

ArticleInfluenza and other respiratory viruses2025

Comparative Analysis of the Evolutionary Dynamics of Seasonal Influenza Viruses in Madagascar Before and Since the Pandemic Period of COVID-19.

Norosoa Harline Razanajatovo, Tsiry Hasina Randriambolamanantsoa, Laurence Randrianasolo, Joelinotahiana Hasina Rabarison, Sitraka Ulrich Raveloson, Baholy Barasaona, Nirina Nantenaina Ranoelison, Arvé Ratsimbazafy, Helisoa Razafimanjato, Fara Adèle Raveloharivony and 7 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Norosoa Harline RazanajatovoNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0003-2063-3932
Tsiry Hasina RandriambolamanantsoaNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Laurence RandrianasoloEpidemiology and Clinical Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Joelinotahiana Hasina RabarisonNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Sitraka Ulrich RavelosonEpidemiology and Clinical Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Baholy BarasaonaDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo, Madagascar.
Nirina Nantenaina RanoelisonEpidemiology and Clinical Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Arvé RatsimbazafyNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Helisoa RazafimanjatoNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Fara Adèle RaveloharivonyDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo, Madagascar.
Aina HarimananaEpidemiology and Clinical Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Rindra RandremananaEpidemiology and Clinical Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0002-6174-8827
Miamina Fidy AnkasitrahanaDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo, Madagascar.
Antso Hasina RaherinandrasanaDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo, Madagascar.
Jean-Michel HeraudNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0003-1107-0859
Philippe DussartNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0002-1931-3037
Vincent LacosteNational Influenza Center, Virology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.ORCID 0000-0002-3173-4053

Funding

NCIRD CDC HHS U51 IP000812United States Agency for International Development #72068719CA00001US Centre for Disease Control and Prevention #U51IP2021000900US Centre for Disease Control and Prevention #U5IP000812-05
6 · The paper itself

Abstract

Madagascar has maintained an influenza surveillance program for decades. Following the emergence of SARS-CoV-2 in 2020, the country implemented strict nonpharmaceutical interventions (NPIs) that disrupted influenza circulation. We studied the evolutionary dynamics of influenza viruses in Madagascar over a 5-year period, spanning both the pre-pandemic and COVID-19 pandemic periods: 2019-2023. We showed that global genetic evolution profiles for A(H1N1)pdm09, A(H3N2), and B/Victoria viruses occurred from the pre-pandemic to the pandemic period of COVID-19 in Madagascar. In addition, we observed distinct patterns of viral re-emergence following the relaxation of COVID-19 containment measures. This study underscores the importance of sustaining continuous surveillance of influenza virus circulation to monitor the emergence of new variants and identify clade-specific isolates. In addition, these results suggest that targeted NPIs could complement vaccination strategies in reducing influenza transmission and should be integrated into a comprehensive approach for effective influenza control.

Indexed as

COVID-19Evolution, MolecularInfluenza, HumanHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza B virusMadagascarPandemicsPhylogenySARS-CoV-2SeasonsCOVID‐19evolutiongeneticsinfluenzaMadagascar

Identifiers

PMID40338114
PMCPMC12058301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.