Evidence map›Paper›PMID 40338089›Full record

ArticleApplied and environmental microbiology2025

Metabolic engineering of

Xu Li, Yanghao Liu, Ling Ma, Wenjing Jiang, Tangen Shi, Lanxiao Li, Changgeng Li, Zhichao Chen, Xiaoguang Fan, Qingyang Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Systems engineering ofSynthetic and systems biotechnology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xu Li *College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Yanghao Liu *College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Ling MaCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Wenjing JiangCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Tangen ShiCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Lanxiao LiCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Changgeng LiCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Zhichao ChenCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.
Xiaoguang Fan *College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.ORCID 0000-0002-1543-0842
Qingyang Xu *College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China.ORCID 0000-0003-1619-3508

Funding

National Key Project for Synthetic Biology 24HHSWSS0001
6 · The paper itself

Abstract

Dopamine (DA) is a high-value metabolic product; however, its biosynthesis has multiple limitations due to metabolic regulation and fermentation strategies. This study aimed to construct a high-yield dopamine-producing IMPORTANCE: In this study, we developed a plasmid-free, defect-free

Indexed as

DopamineEscherichia coliMetabolic EngineeringAnimalsDrosophila melanogasterFermentationDopaminedopamineEscherichia colimetabolic engineering

Identifiers

PMID40338089
PMCPMC12175537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.