Evidence map›Paper›PMID 40337589›Full record

ArticleCureus2025

Massive Scrotal Lymphedema in an Adolescent with Intellectual Disability: A Rare Case of Infection-Related Scrotal Enlargement Requiring Subtotal Scrotectomy.

Muhammad Saqlain, Masood Ur-Rauf Khan Hiraj, Muhammad Ans, Muhammad Usama Ilyas Ahmed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad SaqlainDepartment of General Surgery, Nishtar Hospital, Multan, PAK.
Masood Ur-Rauf Khan HirajDepartment of General Surgery, Nishtar Hospital, Multan, PAK.
Muhammad AnsDepartment of General Surgery, Nishtar Hospital, Multan, PAK.
Muhammad Usama Ilyas AhmedDepartment of General Surgery, Nishtar Hospital, Multan, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An uncommon disorder marked by aberrant fluid accumulation brought on by lymphatic blockage, scrotal lymphedema presents major functional, cosmetic, and hygiene problems. It can be acquired or congenital; the most often occurring causes are infection, persistent inflammation, and filariasis. This case report describes a 17-year-old male patient with intellectual disability who had severe scrotal lymphedema that gradually developed over four years, causing problems with ambulation and hygienic care. Under a clinical examination, the scrotum (40 x 15 cm) was swollen and expanded, hiding the penis but having palpable testes. Ultrasound verified without testicular involvement scrotal wall thickening. After a subtotal scrotectomy preserves the testes, penis, and spermatic cord, scrotal reconstruction was done considering the functional limitation. Chronic inflammatory alterations without filarial organisms revealed by histopathology suggested an etiology connected to infections. The patient healed postoperatively with better mobility and hygienic standards. This example emphasizes the need for early identification and surgical intervention in controlling large scrotal lymphedema to maximize functional and cosmetic results.

Indexed as

chronic inflammationhypertrophyinfection-related lymphedemareconstructionscrotal lymphedema

Identifiers

PMID40337589
PMCPMC12056880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.