Evidence map›Paper›PMID 40337584›Full record

ReviewCureus2025

Enteral Nutrition Interruptions in the Intensive Care Unit: A Systematic Review of Frequency, Causes, and Nutritional Implications.

Sjaak Pouwels, Monica M van Nieuwkoop, Dharmanand Ramnarain

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Artificial intelligence-guided nutritional therapy in the ICU.Current opinion in clinical nutrition and metabolic care · 2026
    Review
  3. Enteral feeding barriers in the intensive care unit of a tertiary hospital in Ghana.The Southern African journal of critical care : the official journal of the Critical Care Society · 2026
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sjaak PouwelsIntensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, NLD.
Monica M van NieuwkoopCritical Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, NLD.
Dharmanand RamnarainIntensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, NLD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteral nutrition interruptions (ENIs) are a major cause of inadequate nutrition goals in critically ill patients. The aim of this systematic review was to provide an update on the various clinical and logistical reasons for ENIs and observe their nutritional implications. PubMed, MEDLINE, Embase, and The Cochrane Library were searched from the inception of each database until March 11, 2024. For data extraction, a structured checklist was used. The initial literature search yielded 522 results. In total, 26 studies were included, comprising 3067 participants. Among the included studies, there were 20 prospective studies, two before-and-after studies, one RCT, and three retrospective studies. The main reasons for ENI were high gastric residual volumes, nasogastric tube dysfunction, and diagnostic and surgical procedures. In conclusion, although the nutritional management of critically ill patients in the ICU has improved drastically, ENIs remain a major problem in clinical practice. Future research should consider different treatments and ICU protocols. Additionally, there is a need for standardized ENI definitions and standardized reporting of the evaluation of energy and/or protein requirements, objectively determining adequate intake, and reporting the causes, frequency, and duration of ENIs.

Indexed as

critical careenteral nutritionenteral nutrition interruptionintensive caremalnutritionunderfeedingundernutrition

Identifiers

PMID40337584
PMCPMC12057588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.