Evidence map›Paper›PMID 40337458›Full record

ArticlePrecision radiation oncology2024

Exploration of individualized neoadjuvant therapy model for operable esophageal cancer: A Surveillance, Epidemiology, and End Results database analysis.

Xingyu Zhou, Jiao Xue, Long Chen, Songbin Qin, Qi Zhao

Abstract read
In one paragraph

Article in Precision radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xingyu ZhouDepartment of Radiation Oncology The First Affiliated Hospital of Soochow University Suzhou China.
Jiao XueDepartment of Radiation Oncology The First Affiliated Hospital of Soochow University Suzhou China.ORCID https://orcid.org/0000-0002-2395-7046
Long ChenDepartment of Radiation Oncology The First Affiliated Hospital of Soochow University Suzhou China.
Songbin QinDepartment of Radiation Oncology The First Affiliated Hospital of Soochow University Suzhou China.
Qi ZhaoDepartment of Radiation Oncology The First Affiliated Hospital of Soochow University Suzhou China.ORCID https://orcid.org/0009-0002-9778-7833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to examine the individualized neoadjuvant therapies for operable esophageal cancer. Methods and Materials: Data of 95,444 patients diagnosed with esophageal cancer between 2010 and 2017 were collected from the Surveillance, Epidemiology, and End Results database. The effectiveness of neoadjuvant chemoradiotherapy (nCRT), neoadjuvant chemotherapy (nCT), and surgery alone was compared in patients with stage II esophageal cancer. Patients with stage III disease were divided into "local invasive type" group (type I, T3N1M0, T4N0-1M0) and "regional metastatic type" group (type II, T1-2N2-3M0) according to the tumor invasion pattern. The effectiveness of nCRT and nCT in different patterns was compared. Results: In 2,706 patients with stage II disease, a statistical difference was observed in the overall survival (OS) between nCRT (85.1%), nCT (3.0%), and surgery alone (11.9%, Conclusions: nCRT is recommended for stage II esophageal cancer. In patients with stage III, those with "local invasive type" may greatly benefit from nCRT, while those with "regional metastatic type" may greatly benefit from nCT.

Indexed as

Esophageal cancerIndividualized therapyNeoadjuvant therapy

Identifiers

PMID40337458
PMCPMC11934889

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.