ReviewAnnals of medicine and surgery (2012)2025
Exploring neonatal brain tumors: a narrative review about epidemiology, classification, and management.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Primary Intracranial High Grade Congenital Glial Lesions (PIHGCL): A systematic review of case reports from 1985 to 2025.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- Infantile brainstem tumors presenting with recurrent pneumonia and dysphagia: a report of two cases and literature review.BMC pediatrics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neonatal brain tumors (NBTs) are rare, with specific characteristics distinguishing them from tumors in older children. NBTs occur in the first 28 days of life with a low incidence rate. They present unique histological features, with teratomas and gliomas being the most relevant types of NBTs. The most common clinical finding is macrocephaly and hydrocephaly, but non-specific symptoms can also occur. Researchers illustrated multiple risk factors predominantly carcinogens and genetic factors. Managing these tumors is challenging, with surgery being the gold standard for treatment whereas the use of chemotherapy and radiotherapy is risky with this age group. Thus, balancing between aggressive intervention and adverse effects is crucial. This review will be relevant to clinicians and researchers interested in understanding the epidemiology, classification, clinical features, diagnostic features, and management options of NBTs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.