Evidence map›Paper›PMID 40337267›Full record

ReviewPrecision radiation oncology2023

Application of radiomics in lung immuno-oncology.

Weisi Yan, Chen Quan, Waleed F Mourad, Jianda Yuan, Zheng Shi, Jun Yang, Qiuxia Lu, Jie Zhang

Abstract readReview
In one paragraph

Review in Precision radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Application of radiomics in lung immuno-oncology.Precision radiation oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weisi YanBaptist Health System Lexington Kentucky USA.ORCID https://orcid.org/0000-0001-5274-160X
Chen QuanCity of Hope Comprehensive Cancer Center Duarte California USA.
Waleed F MouradDepartment of Radiation Medicine University of Kentucky Lexington Kentucky USA.
Jianda YuanTranslational Oncology at Merck & Co Kenilworth New Jersey USA.
Zheng ShiUMC Health System Lubbock Texas USA.
Jun YangFoshan Chancheng Hospital Foshan Guangdong China.ORCID https://orcid.org/0000-0002-2861-0885
Qiuxia LuFoshan Chancheng Hospital Foshan Guangdong China.
Jie ZhangDepartment of Radiology University of Kentucky Lexington Kentucky USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiomics is a rapidly evolving field of research that extracts and analyzes quantitative features within medical images. Those features are termed as radiomic features that can characterize a tumor in a comprehensive and quantitative manner with regard to its internal structure and heterogeneity. Radiomic features can be used, alone or in combination with demographic, histological, genomic, or proteomic data, for predicting prognosis or treatment response. Immunotherapy, or immune-oncology, is the study of cancer treatment by taking advantage of the body's immune system to prevent, control, and eliminate cancer. In this review, we first provide a brief introduction to both radiomics and immune-oncology in lung cancer. Then, we discuss the need for developing immune-oncology biomarkers, and the advantages of radiomics in identifying biomarkers related to immunotherapy. We also discuss potential areas in and out of tumors, such as the intra-tumoral hypoxic region and tumor microenvironment, where radiomic markers might be extracted, as well as a potential application of radiomic biomarkers in clinical lung cancer management. Finally, we present radiation and immune modulation in non-small cell lung cancer, clinical trials and their design to incorporate radiomic biomarkers, and radiomics-guided precision radiation therapy.

Indexed as

immune modulationnon‐small cell lung cancerradiationradiomics

Identifiers

PMID40337267
PMCPMC11935008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.