Evidence map›Paper›PMID 40337265›Full record

ArticlePrecision radiation oncology2023

Whole-breast irradiation with lumpectomy cavity boost and regional nodal irradiation: Dosimetric comparison of 3D-CRT using sequential boost and dual partial-arc VMAT using simultaneous integrated boost.

Avinash Poojari, Shantanu Sapru, Rohini Khurana, Madhup Rastogi, Rahat Hadi, Ajeet Kumar Gandhi, Surendra Mishra, Anoop Srivastava, Avinav Bharati

Abstract read
In one paragraph

Article in Precision radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Avinash PoojariRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.ORCID https://orcid.org/0000-0002-7417-4148
Shantanu SapruRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Rohini KhuranaRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.ORCID https://orcid.org/0000-0002-4493-1742
Madhup RastogiRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Rahat HadiRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Ajeet Kumar GandhiRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Surendra MishraRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Anoop SrivastavaRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.
Avinav BharatiRadiation Oncology Dr Ram Manohar Lohia Institute of Medical Sciences.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare volumetric modulated arc therapy (VMAT) with simultaneous tumor bed boost (dpSIB-VMAT) to the whole breast and regional nodal irradiation (RNI) against standard three-dimensional conformal radiotherapy plus RNI with sequential tumor bed boost (3D-CRT-seqB). Methods: Thirty patients who underwent breast cancer surgery (BCS) with axillary lymph node dissection (ALND) were enrolled. Two plans were generated for each case: (1) dpSIB-VMAT, and (2) 3D-CRT-seqB plans. Planning target volume (PTV)-Breast and PTV-Nodes were prescribed at a dose of 50 Gy in 25 fractions in both plans. PTV-Boost was prescribed at a dose of 60 Gy in 25 fractions simultaneously in the dpSIB-VMAT plans, whereas it was planned sequentially in the 3D-CRT-seqB plans at 10 Gy in 5 fractions. Dosimetric parameters were compared between the two plans. Results: Both plans achieved the target coverage. D Conclusion: Dosimetrically, dpSIB-VMAT reduced doses to the ipsilateral lung and heart (in left breast but not right breast cases) compared to 3D-CRT-seqB plans for adequate target coverage.

Indexed as

Breast cancerbreast conservation therapydosimetrysequential boostthree‐dimensional conformal radiotherapyvolumetric modulated arc therapy

Identifiers

PMID40337265
PMCPMC11934988

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.