Evidence map›Paper›PMID 40337264›Full record

ArticlePrecision radiation oncology2023

Characterization of Gafchromic

Fada Guan, Huixiao Chen, Emily Draeger, Yuting Li, Resat Aydin, Christopher J Tien, Zhe Chen

Abstract read
In one paragraph

Article in Precision radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. On temporal evolution of the response of EBT4 radiochromic films.Journal of applied clinical medical physics · 2026
    Article
  6. Activity-dependent transit dose assessment inPrecision radiation oncology · 2025
    Article
  7. Characterizing the motion management system accuracy on a 1.5T MR-Linac.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Characterization of GafchromicPrecision radiation oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fada GuanDepartment of Therapeutic Radiology Yale University School of Medicine New Haven Connecticut USA.ORCID https://orcid.org/0000-0001-8477-7391
Huixiao ChenDepartment of Therapeutic Radiology Yale University School of Medicine New Haven Connecticut USA.
Emily DraegerDepartment of Therapeutic Radiology Yale University School of Medicine New Haven Connecticut USA.
Yuting LiDepartment of Radiation Physics The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard Houston Texas USA.
Resat AydinAshland Specialty Ingredients G.P. Bridgewater New Jersey USA.
Christopher J TienDepartment of Therapeutic Radiology Yale University School of Medicine New Haven Connecticut USA.
Zhe ChenDepartment of Therapeutic Radiology Yale University School of Medicine New Haven Connecticut USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: A newly developed Gafchromic Methods: In the beam energy dependence experiments, 6 MV and 15 MV photon beams, 6 MeV, 12 MeV and 20 MeV electron beams, 120 kVp and two 250 kVp x-ray beams (with different half-layer values) were selected, representing different clinical beam energies and radiation types. In the noise and SNR analyses, only the 6 MV photon beam was selected as the representative to compare between EBT4 and EBT3 models. Results: The energy dependence test results showed that there was a slight difference (<2% at most dose levels) in the dose response among the clinical MV photons and MeV electrons. However, a large deviation (>10%) in the dose response was found for the 120 kVp x-ray beam. For the two 250 kVp x-ray beams, the difference in the dose response was moderate (<5%), but not negligible. The noise and SNR results showed a reduced noise and strengthened SNR in EBT4. Conclusion: We conclude that the EBT4 film has a minimal energy dependence for MV photon and MeV electron beams but has a notable energy dependence for kilovoltage x-ray beams, and the vendor-stated features of the reduced noise and improved SNR in EBT4 are validated.

Indexed as

EBT4GafchromicTM filmphoton and electron beams

Identifiers

PMID40337264
PMCPMC11935191

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.