Evidence map›Paper›PMID 40337206›Full record

ArticlePrecision radiation oncology2023

Dosimetric and Radiobiological Impact of Flattening Filter-Free Beam and Dose Calculation Algorithm Using RapidArc Plans for Cervical Cancer Treatment.

Sumanta Manna, Sharad Singh, Pramod Kumar Gupta, Ragul T

Abstract read
In one paragraph

Article in Precision radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sumanta MannaMedical Physics Kalyan Singh Super Specialty Cancer Institute Lucknow Uttar Pradesh INDIA.ORCID https://orcid.org/0000-0003-4079-1591
Sharad SinghRadiation Oncology Kalyan Singh Super Specialty Cancer Institute Lucknow Uttar Pradesh INDIA.ORCID https://orcid.org/0009-0007-0607-152X
Pramod Kumar GuptaRadiation Oncology Kalyan Singh Super Specialty Cancer Institute Lucknow Uttar Pradesh INDIA.ORCID https://orcid.org/0000-0003-3210-1554
Ragul TMedical Physics Kalyan Singh Super Specialty Cancer Institute Lucknow Uttar Pradesh INDIA.ORCID https://orcid.org/0009-0007-9004-7329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this study is to quantify the potential benefits of a flattening filter-free (FFF) beam and implement a dose-computation algorithm for cervical radiotherapy through dosimetric and radiobiological analyses using RapidArc. Methods: Thirty-three patients were enrolled, and four RapidArc plans were created for each patient using a dual-arc flattening filter and 6-MV FFF photon beams for the two calculation algorithms. Homogeneity index (HI), conformity index (CI), target coverage, monitor units (MUs), and organ-at-risk (OAR) dosimetric characteristics were compared between the plans. Radiobiological characteristics and normal tissue complication probability (NTCP) scores were computed for the OAR using different biological models. Results: No significant differences were observed in the D Conclusion: The current study recommends FFF beams for better conformity, comparable dose coverage for the target, and OAR sparing invariable to the dose computation algorithm. The difference in the NTCP score for OAR was minimal with the FFF beam.

Indexed as

Acuros XBanisotropic analytical algorithmcervical cancerdosimetric evaluationflattening filterflattening filter‐free

Identifiers

PMID40337206
PMCPMC11935009

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.